HIT-result

Target Description

Type	Detail
Target ID	T88A0X
Protein Name	Substance-P receptor
Uniprot ID	P25103
Protein Name Alias	SPR; NK-1 receptor; NK-1R; Tachykinin receptor 1
Gene ID	6869
Gene Symbol	TACR1
Gene Alias	NK1R; TAC1R
TTD	T47094: Successful target
Pfam	PF00001
GO	1902093:positive regulation of flagellated sperm motility 0036126:sperm flagellum 0016496:substance P receptor activity 0004995:tachykinin receptor activity 0097225:sperm midpiece 0007200:phospholipase C-activating G protein-coupled receptor signaling pathway 0006954:inflammatory response 0070472:regulation of uterine smooth muscle contraction 0061827:sperm head 0048265:response to pain 0009582:detection of abiotic stimulus 0007217:tachykinin receptor signaling pathway 0005887:integral component of plasma membrane 0007204:positive regulation of cytosolic calcium ion concentration 0005886:plasma membrane 0007186:G protein-coupled receptor signaling pathway
PDB	2KS9 ; 2KSA ; 6HLP ; 2KSB ; 6E59 ; 6HLL ; 6HLO
Drugbank	DB12436 ; DB05790 ; DB05421 ; DB09291 ; DB00193 ; DB04894 ; DB01221 ; DB11949 ; DB05072 ; DB00673 ; DB05418 ; DB09048 ; DB05466 ; DB14019 ; DB06634
KEGG	hsa:6869

Type

Detail

Target ID

T88A0X

Protein Name

Substance-P receptor

Uniprot ID

P25103

Protein Name Alias

SPR; NK-1 receptor; NK-1R; Tachykinin receptor 1

Gene ID

6869

Gene Symbol

TACR1

Gene Alias

NK1R; TAC1R

TTD

T47094: Successful target

Pfam

PF00001

1902093:positive regulation of flagellated sperm motility

0036126:sperm flagellum

0016496:substance P receptor activity

0004995:tachykinin receptor activity

0097225:sperm midpiece

0007200:phospholipase C-activating G protein-coupled receptor signaling pathway

0006954:inflammatory response

0070472:regulation of uterine smooth muscle contraction

0061827:sperm head

0048265:response to pain

0009582:detection of abiotic stimulus

0007217:tachykinin receptor signaling pathway

0005887:integral component of plasma membrane

0007204:positive regulation of cytosolic calcium ion concentration

0005886:plasma membrane

0007186:G protein-coupled receptor signaling pathway

PDB

2KS9 ; 2KSA ; 6HLP ; 2KSB ; 6E59 ; 6HLL ; 6HLO

Drugbank

DB12436 ; DB05790 ; DB05421 ; DB09291 ; DB00193 ; DB04894 ; DB01221 ; DB11949 ; DB05072 ; DB00673 ; DB05418 ; DB09048 ; DB05466 ; DB14019 ; DB06634

KEGG

hsa:6869

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0854	Zi Wei Gen Pi	紫葳根皮	NA	Campsis grandiflora
H0123	La Jiao Liu Jin Gao	辣椒流浸膏	Bush redpepper	Capsicum frutescens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0242	Bei Sha Shen Liu Jin Gao	北沙参流浸膏	Glehnia littoralis	Glehnia littoralis
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0119	La Jiao	辣椒	Bush redpepper	Capsicum frutescens
H0227	Mang Guo Ye	芒果叶	Mango leaf	Mangifera indica
H0121	La Jiao Jin Chu Ye	辣椒浸出液	Bush redpepper	Capsicum frutescens
H0239	Bei Sha Shen	北沙参	Coastal glehnia	Glehnia littoralis
H0122	La Jiao Jin Gao	辣椒浸膏	Bush redpepper	Capsicum frutescens

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 10)