HIT-result

Type	Detail
Target ID	T88LD4
Protein Name	Histone-lysine N-methyltransferase NSD2
Uniprot ID	O96028
Protein Name Alias	EC 2.1.1.357; Multiple myeloma SET domain-containing protein; MMSET; Nuclear SET domain-containing protein 2; Protein trithorax-5; Wolf-Hirschhorn syndrome candidate 1 protein
Gene ID	7468
Gene Symbol	NSD2
Gene Alias	KIAA1090; MMSET; TRX5; WHSC1
TTD	NA
Pfam	PF00856 ; PF17907 ; PF00855 ; PF00505 ; PF17982
GO	0005634:nucleus 0070201:regulation of establishment of protein localization 0006302:double-strand break repair 0043565:sequence-specific DNA binding 0006355:regulation of transcription, DNA-templated 0003682:chromatin binding 0003289:atrial septum primum morphogenesis 0005737:cytoplasm 0060348:bone development 0000785:chromatin 0005730:nucleolus 0046975:histone methyltransferase activity (H3-K36 specific) 0006303:double-strand break repair via nonhomologous end joining 0003290:atrial septum secundum morphogenesis 0000122:negative regulation of transcription by RNA polymerase II 2001032:regulation of double-strand break repair via nonhomologous end joining 0048298:positive regulation of isotype switching to IgA isotypes 0005654:nucleoplasm 0046872:metal ion binding 0003149:membranous septum morphogenesis 0034770:histone H4-K20 methylation
PDB	5VC8 ; 6XCG ; 5LSU ; 7CRO ; 6UE6
Drugbank	NA
KEGG	hsa:7468

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description