Target Description
| Type | Detail |
|---|---|
| Target ID | T88MHO |
| Protein Name | Free fatty acid receptor 1 |
| Uniprot ID |
O14842 |
| Protein Name Alias | G-protein coupled receptor 40 |
| Gene ID |
2864 |
| Gene Symbol | FFAR1 |
| Gene Alias | GPR40 |
| TTD | T25608: Clinical Trial target |
| Pfam | PF00001 |
| GO |
0045125:bioactive lipid receptor activity
0007186:G protein-coupled receptor signaling pathway 0042593:glucose homeostasis 0005887:integral component of plasma membrane 0004930:G protein-coupled receptor activity 0032024:positive regulation of insulin secretion 0050796:regulation of insulin secretion 0030073:insulin secretion 0007204:positive regulation of cytosolic calcium ion concentration 0070542:response to fatty acid 0008289:lipid binding 0051928:positive regulation of calcium ion transport 0032691:negative regulation of interleukin-1 beta production 0005886:plasma membrane |
| PDB | 5TZR ; 5KW2 ; 5TZY ; 4PHU |
| Drugbank | DB00159 |
| KEGG | hsa:2864 |
