Target Description

Type Detail
Target ID T94HJF
Protein Name Replication protein A 70 kDa DNA-binding subunit
Uniprot ID P27694
Protein Name Alias RP-A p70;  Replication factor A protein 1;  RF-A protein 1;  Single-stranded DNA-binding protein
Gene ID 6117
Gene Symbol RPA1
Gene Alias REPA1;  RPA70
TTD NA
Pfam PF08646 ; PF16900 ; PF04057 ; PF01336
GO
0006298:mismatch repair

0034502:protein localization to chromosome

0005634:nucleus

0006294:nucleotide-excision repair, preincision complex assembly

0006295:nucleotide-excision repair, DNA incision, 3'-to lesion

1900034:regulation of cellular response to heat

0006268:DNA unwinding involved in DNA replication

0007004:telomere maintenance via telomerase

0006283:transcription-coupled nucleotide-excision repair

0016605:PML body

0000724:double-strand break repair via homologous recombination

0070987:error-free translesion synthesis

0005662:DNA replication factor A complex

0006310:DNA recombination

0000781:chromosome, telomeric region

0006270:DNA replication initiation

0006284:base-excision repair

0003684:damaged DNA binding

1901796:regulation of signal transduction by p53 class mediator

0051321:meiotic cell cycle

0006289:nucleotide-excision repair

0006281:DNA repair

0006287:base-excision repair, gap-filling

0019985:translesion synthesis

0032201:telomere maintenance via semi-conservative replication

0036297:interstrand cross-link repair

0033683:nucleotide-excision repair, DNA incision

0098505:G-rich strand telomeric DNA binding

0006260:DNA replication

0042276:error-prone translesion synthesis

0042769:DNA damage response, detection of DNA damage

0006261:DNA-dependent DNA replication

0043047:single-stranded telomeric DNA binding

0003697:single-stranded DNA binding

0006297:nucleotide-excision repair, DNA gap filling

0090734:site of DNA damage

0005654:nucleoplasm

0046872:metal ion binding

0006296:nucleotide-excision repair, DNA incision, 5'-to lesion

0000723:telomere maintenance

0006293:nucleotide-excision repair, preincision complex stabilization

0006974:cellular response to DNA damage stimulus

PDB 4R4C ; 4O0A ; 4R4O ; 4IJH ; 2B29 ; 4IPD ; 4LUZ ; 1L1O ; 4IJL ; 4IPH ; 4LUV ; 4LW1 ; 4NB3 ; 1EWI ; 5N85 ; 5EAY ; 4R4T ; 4IPC ; 4R4Q ; 1FGU ; 4LUO ; 2B3G ; 4R4I ; 1JMC ; 5E7N ; 4IPG ; 4LWC ; 5N8A
Drugbank NA
KEGG hsa:6117

Related Compounds  (Total: 1)

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C0913
Name: Ap


Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens