Target Description

Type Detail
Target ID T95DSF
Protein Name Tuberin
Uniprot ID P49815
Protein Name Alias Tuberous sclerosis 2 protein
Gene ID 7249
Gene Symbol TSC2
Gene Alias TSC4
TTD NA
Pfam PF02145 ; PF11864 ; PF03542
GO
0005634:nucleus

0008104:protein localization

0032007:negative regulation of TOR signaling

0014067:negative regulation of phosphatidylinositol 3-kinase signaling

0005829:cytosol

1901525:negative regulation of mitophagy

0046626:regulation of insulin receptor signaling pathway

0046627:negative regulation of insulin receptor signaling pathway

0008285:negative regulation of cell population proliferation

0014069:postsynaptic density

0001843:neural tube closure

0043276:anoikis

0007507:heart development

0051056:regulation of small GTPase mediated signal transduction

0006606:protein import into nucleus

0051898:negative regulation of protein kinase B signaling

0051879:Hsp90 protein binding

0048471:perinuclear region of cytoplasm

0005764:lysosome

0030178:negative regulation of Wnt signaling pathway

0016020:membrane

0016192:vesicle-mediated transport

0005096:GTPase activator activity

0031267:small GTPase binding

0043491:protein kinase B signaling

0050918:positive chemotaxis

0019902:phosphatase binding

0033596:TSC1-TSC2 complex

0005794:Golgi apparatus

0030100:regulation of endocytosis

0042803:protein homodimerization activity

0005737:cytoplasm

0006897:endocytosis

0016032:viral process

0051726:regulation of cell cycle

0048009:insulin-like growth factor receptor signaling pathway

0016239:positive regulation of macroautophagy

0006469:negative regulation of protein kinase activity

PDB 7DL2
Drugbank NA
KEGG hsa:7249

Related Compounds  (Total: 1)

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C1265
Name: Curcumin


Related Herbs  (Total: 7)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1093 Gao Liang Jiang You高良姜油 Lesser galangalAlpinia officinarum
H0142 Liang Jiang良姜 NAAlpinia officinarum
H1092 Gao Liang Jiang高良姜 Lesser galangalAlpinia officinarum
H0761 Yu Jin郁金 AromaticTurmericCurcuma aromatica
H0556 Tie Xian Cao铁线草 NAAdiantum capillus-veneris
H0895 Chuan Yu Jin川郁金 TurmericCurcuma longa
H0028 Jiang Huang姜黄 Common turmericCurcuma longa