Target Description

Type Detail
Target ID T95M54
Protein Name Programmed cell death protein 4
Uniprot ID Q53EL6
Protein Name Alias Neoplastic transformation inhibitor protein;  Nuclear antigen H731-like;  Protein 197/15a
Gene ID 27250
Gene Symbol PDCD4
Gene Alias H731
TTD NA
Pfam PF02847
GO
0005634:nucleus

0030509:BMP signaling pathway

0005829:cytosol

1901224:positive regulation of NIK/NF-kappaB signaling

0071222:cellular response to lipopolysaccharide

2000353:positive regulation of endothelial cell apoptotic process

1905461:positive regulation of vascular associated smooth muscle cell apoptotic process

0006915:apoptotic process

0045892:negative regulation of transcription, DNA-templated

1904706:negative regulation of vascular associated smooth muscle cell proliferation

1905064:negative regulation of vascular associated smooth muscle cell differentiation

0045786:negative regulation of cell cycle

1904761:negative regulation of myofibroblast differentiation

0043066:negative regulation of apoptotic process

0060940:epithelial to mesenchymal transition involved in cardiac fibroblast development

0050729:positive regulation of inflammatory response

0003723:RNA binding

0005737:cytoplasm

0035722:interleukin-12-mediated signaling pathway

0043508:negative regulation of JUN kinase activity

1900016:negative regulation of cytokine production involved in inflammatory response

0007569:cell aging

PDB 2KZT ; 2GGF ; 3EIJ ; 2RG8 ; 2ZU6
Drugbank NA
KEGG hsa:27250

Related Compounds  (Total: 1)

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C0436
Name: Testosterone


Related Herbs  (Total: 4)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0761 Yu Jin郁金 AromaticTurmericCurcuma aromatica
H0697 Ya Ma Zi亚麻子 Common flax seedLinum usitatissimum
H0847 Zi He Che紫河车 Human placentaHomo sapiens