HIT-result

Type	Detail
Target ID	T95XHB
Protein Name	Integrin alpha-IIb
Uniprot ID	P08514
Protein Name Alias	GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD antigen CD41
Gene ID	3674
Gene Symbol	ITGA2B
Gene Alias	GP2B; ITGAB
TTD	T50688: Successful target
Pfam	PF00357 ; PF08441 ; PF01839
GO	0070062:extracellular exosome 0009986:cell surface 0007229:integrin-mediated signaling pathway 0070527:platelet aggregation 0008305:integrin complex 0072562:blood microparticle 0005925:focal adhesion 0002576:platelet degranulation 0046872:metal ion binding 0002687:positive regulation of leukocyte migration 0042802:identical protein binding 0009897:external side of plasma membrane 0031092:platelet alpha granule membrane 0070051:fibrinogen binding 0005886:plasma membrane 0007160:cell-matrix adhesion 0050840:extracellular matrix binding 0030198:extracellular matrix organization 0045652:regulation of megakaryocyte differentiation
PDB	1RN0 ; 1DPK ; 1UV9 ; 4CAK ; 2K1A ; 3FCU ; 3NIG ; 4Z7Q ; 3FCS ; 3ZE2 ; 3NID ; 2VDK ; 1S4W ; 1KUP ; 2MTP ; 2VDO ; 3ZE0 ; 3T3P ; 2KNC ; 3ZE1 ; 2K9J ; 2VDN ; 3ZDZ ; 5HDB ; 1DPQ ; 2VDM ; 3ZDY ; 6V4P ; 2VC2 ; 3T3M ; 3NIF ; 1TYE ; 3ZDX ; 4Z7O ; 1KUZ ; 1M8O ; 2VDQ ; 2VDR ; 2VDL ; 2N9Y ; 2VDP ; 1JX5 ; 4Z7N
Drugbank	DB04863 ; DB06472 ; DB00775 ; DB00054
KEGG	hsa:3674

Target Description