HIT-result

Target Description

Type	Detail
Target ID	T95Z7B
Protein Name	Polycomb complex protein BMI-1
Uniprot ID	P35226
Protein Name Alias	Polycomb group RING finger protein 4; RING finger protein 51
Gene ID	648
Gene Symbol	BMI1
Gene Alias	PCGF4; RNF51
TTD	T74066: Research target
Pfam	PF16207
GO	0005634:nucleus 0036353:histone H2A-K119 monoubiquitination 0051443:positive regulation of ubiquitin-protein transferase activity 0010468:regulation of gene expression 0045814:negative regulation of gene expression, epigenetic 0000151:ubiquitin ligase complex 0048146:positive regulation of fibroblast proliferation 0007379:segment specification 0005829:cytosol 0031519:PcG protein complex 1990841:promoter-specific chromatin binding 0030097:hemopoiesis 0035102:PRC1 complex 0016604:nuclear body 0000122:negative regulation of transcription by RNA polymerase II 0071535:RING-like zinc finger domain binding 0008270:zinc ion binding 0005654:nucleoplasm 0006342:chromatin silencing 0070317:negative regulation of G0 to G1 transition
PDB	2NA1 ; 3RPG ; 5FR6 ; 2H0D ; 4R8P
Drugbank	NA
KEGG	hsa:648 ; hsa:100532731

Type

Detail

Target ID

T95Z7B

Protein Name

Polycomb complex protein BMI-1

Uniprot ID

P35226

Protein Name Alias

Polycomb group RING finger protein 4; RING finger protein 51

Gene ID

648

Gene Symbol

BMI1

Gene Alias

PCGF4; RNF51

TTD

T74066: Research target

Pfam

PF16207

0005634:nucleus

0036353:histone H2A-K119 monoubiquitination

0051443:positive regulation of ubiquitin-protein transferase activity

0010468:regulation of gene expression

0045814:negative regulation of gene expression, epigenetic

0000151:ubiquitin ligase complex

0048146:positive regulation of fibroblast proliferation

0007379:segment specification

0005829:cytosol

0031519:PcG protein complex

1990841:promoter-specific chromatin binding

0030097:hemopoiesis

0035102:PRC1 complex

0016604:nuclear body

0000122:negative regulation of transcription by RNA polymerase II

0071535:RING-like zinc finger domain binding

0008270:zinc ion binding

0005654:nucleoplasm

0006342:chromatin silencing

0070317:negative regulation of G0 to G1 transition

PDB

2NA1 ; 3RPG ; 5FR6 ; 2H0D ; 4R8P

Drugbank

KEGG

hsa:648 ; hsa:100532731

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1093	Gao Liang Jiang You	高良姜油	Lesser galangal	Alpinia officinarum
H0142	Liang Jiang	良姜	NA	Alpinia officinarum
H1206	Hu Lu Ke	葫芦壳	NA	Lagenaria siceraria
H0480	Shu She	树舌	Tongue-on-tree	Ganoderma applanatum
H1092	Gao Liang Jiang	高良姜	Lesser galangal	Alpinia officinarum
H0761	Yu Jin	郁金	AromaticTurmeric	Curcuma aromatica
H0556	Tie Xian Cao	铁线草	NA	Adiantum capillus-veneris
H0895	Chuan Yu Jin	川郁金	Turmeric	Curcuma longa
H0028	Jiang Huang	姜黄	Common turmeric	Curcuma longa

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 9)