HIT-result

Type	Detail
Target ID	T99S78
Protein Name	Interferon alpha/beta receptor 2
Uniprot ID	P48551
Protein Name Alias	IFN-R-2; IFN-alpha binding protein; IFN-alpha/beta receptor 2; Interferon alpha binding protein; Type I interferon receptor 2
Gene ID	3455
Gene Symbol	IFNAR2
Gene Alias	IFNABR; IFNARB
TTD	T06421: Successful target
Pfam	PF09294 ; PF01108
GO	0005886:plasma membrane 0009615:response to virus 0019962:type I interferon binding 0051607:defense response to virus 0005887:integral component of plasma membrane 0019901:protein kinase binding 0005615:extracellular space 0019221:cytokine-mediated signaling pathway 0007259:receptor signaling pathway via JAK-STAT 0035456:response to interferon-beta 0004905:type I interferon receptor activity 0060337:type I interferon signaling pathway 0060338:regulation of type I interferon-mediated signaling pathway 0005576:extracellular region 0035455:response to interferon-alpha 0007166:cell surface receptor signaling pathway 0016021:integral component of membrane 0004896:cytokine receptor activity
PDB	3S8W ; 1N6U ; 3SE4 ; 2KZ1 ; 3S9D ; 2HYM ; 3SE3 ; 2LAG ; 1N6V
Drugbank	DB05472 ; DB00018 ; DB00068 ; DB00008 ; DB00034 ; DB00011 ; DB00022 ; DB00105 ; DB06152 ; DB00069 ; DB00060
KEGG	hsa:3455

Target Description