Compound Description
| ID: C0257 | Common name: Obacunone |
| IUPAC: NA | CAS: CAS:751-03-1 |
| Chembl ID: CHEMBL404140 | Pubchem ID: CID:119041 |
| Formula: C26H30O7 | TCM-ID: TCMC1771 |
| Smiles: O=C1C=C[C@]2([C@H](C(O1)(C)C)CC(=O)[C@@]1([C@@H]2CC[C@@]2([C@]31O[C@@H]3C(=O)O[C@H]2c1ccoc1)C)C)C | |
| Alias:
Obacunoic acid, ε-lactone;
Obacunone; Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aαH,4bH,6H)-trione, 1α-(3-furyl)-1,6aα,7,11a,11bα,12,13,13a-octahydro-4bβ,7,7,11aβ,13aα-pentamethyl-; (1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(3-Furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyloxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione; 14,15 |
Structure:
|
Related Targets (Total: 1)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T74P7I | G-protein coupled bile acid receptor 1 | GPBAR1 |
Q8TDU6 |
A | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 14)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0652 | Xiang Yuan Pi | 香橼皮 | Wilson citron | Citrus medica |
| H1228 | Huang Bai | 黄柏 | Amur corktree | Phellodendron amurense |
| H0704 | Yan Guan Huang Bai | 盐关黄柏 | Amur cork tree | Phellodendron amurense |
| H0142 | Liang Jiang | 良姜 | NA | Alpinia officinarum |
| H1230 | Huang Bai Fen | 黄柏粉 | Amur corktree | Phellodendron amurense |
| H0088 | Ju He | 橘核 | Tangerine seed | Citrus reticulata |
| H0651 | Xiang Yuan | 香橼 | Wilson citron | Citrus medica |
| H1092 | Gao Liang Jiang | 高良姜 | Lesser galangal | Alpinia officinarum |
| H0093 | Ju Pi | 橘皮 | Tangerine pericarp | Citrus reticulata |
| H0604 | Wu Wei Teng | 五味藤 | NA | Securidaca inappendiculata |
| H0089 | Ju Hong | 橘红 | NA | Citri exocarpium rubrum |
| H1115 | Guan Huang Bai | 关黄柏 | Amur cork tree | Phellodendron amurense |
| H1093 | Gao Liang Jiang You | 高良姜油 | Lesser galangal | Alpinia officinarum |
| H1231 | Huang Bai Tan | 黄柏炭 | Amur corktree | Phellodendron amurense |
Ckey description of the interaction between compound and target