Compound Description
| ID: C0323 | Common name: Pregnenolone |
| IUPAC: 1-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone | CAS: CAS:145-13-1 |
| Chembl ID: CHEMBL253363 | Pubchem ID: CID:8955 |
| Formula: C21H32O2 | TCM-ID: TCMC1935 |
| Smiles: O[C@H]1CC[C@]2(C(=CC[C@@H]3[C@@H]2CC[C@]2([C@H]3CC[C@@H]2C(=O)C)C)C1)C | |
| Alias:
Pregn-5-en-20-one, 3β-hydroxy-;
(3β)-3-Hydroxypregn-5-en-20-one; 17β-[1-Ketoethyl]-Δ5-androsten-3β-ol; 3β-Hydroxy-5-en-20-one; 3β-Hydroxy-5-pregnene-20-one; 3β-Hydroxy-Δ5-pregnen-20-one; 3β-Hydroxypregn-5-en-20-one; 5-Pregnenolone; Arthenolone; Bina-Skin; Enelone; NSC 1616; NSC 18158; Natolone; Pregn-5-en-3β-ol-20-one; Pregn-5-ene-3β-ol-20-one; Pregnelon; Pregnenolone; Pregnenolone (progesterone precursor); Pregnetan; Pregneton; Pregnolon; Prenolon; Regnosone; Skinostelon; Δ5-Pregnen-3β-ol-20-one; Δ5-Pregnene-3β-ol-20-one; Δ5-Pregnenolone |
Structure:
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Related Targets (Total: 6)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T50SX0 | Nuclear receptor subfamily 1 group I member 2 | NR1I2 |
O75469 |
A | 2 Reference(s) |
| T88QEV | Transient receptor potential cation channel subfamily M member 3 | TRPM3 |
Q9HCF6 |
A | 1 Reference(s) |
| T70U24 | Sigma non-opioid intracellular receptor 1 | SIGMAR1 |
Q99720 |
A | 1 Reference(s) |
| T32KWK | CAP-Gly domain-containing linker protein 1 | CLIP1 |
P30622 |
B | 1 Reference(s) |
| T69VTW | Syntaxin-binding protein 1 | STXBP1 |
P61764 |
B | 1 Reference(s) |
| T14ENF | Microtubule-associated protein 2 | MAP2 |
P11137 |
B | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 9)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0919 | Cui Yun Cao | 翠云草 | Hooked spikemoss | Selaginella uncinata |
| H1090 | Gao Ben | 藁本 | Chinese ligusticum | Ligusticum sinense |
| H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
| H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
| H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
| H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0060 | Jin Si Ku Lian | 金丝苦楝 | NA | Cardiospermum halicacabum |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
Ckey description of the interaction between compound and target