Compound Description
| ID: C0370 | Common name: Rhynchophylline |
| IUPAC: methyl (E)-2-[(3R,6'R,7'S,8'aS)-6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate | CAS: CAS:76-66-4 |
| Chembl ID: CHEMBL519266 | Pubchem ID: CID:5281408 |
| Formula: C22H28N2O4 | TCM-ID: TCMC2015 |
| Smiles: CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O | |
| Alias:
Corynoxan-16-carboxylic acid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (7β,16E,20α)-;
Rhyncophylline; Mitrinermin; Mitrinermine; NSC 21731; Rhynchophyllin; Rhynchophylline; Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethyl-1,2,2',3',6',7',8',8'a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, [1'R-[1'α,6'β,7'α(E),8'aβ]]- |
Structure:
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Related Targets (Total: 2)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T86CQC | Glutamate receptor ionotropic, NMDA 1 | GRIN1 |
Q05586 |
A | 1 Reference(s) |
| T42WKC | Ephrin type-A receptor 4 | EPHA4 |
P54764 |
A | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 1)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1099 | Gou Teng | 钩藤 | Sharpleaf gambirplant | Uncaria rhynchophylla |
Ckey description of the interaction between compound and target