Compound Description
| ID: C0425 | Common name: Tangeretin |
| IUPAC: 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)chromen-4-one | CAS: CAS:481-53-8 |
| Chembl ID: CHEMBL73930 | Pubchem ID: CID:68077 |
| Formula: C20H20O7 | TCM-ID: TCMC2123 |
| Smiles: COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C(=C3OC)OC)OC)OC | |
| Alias:
Flavone, 4',5,6,7,8-pentamethoxy-;
Tangeretin; 5,6,7,8-Tetramethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; 4',5,6,7,8-Pentamethoxyflavone; 5,6,7,8,4'-Pentamethoxyflavone; NSC 53909; NSC 618905; Ponkanetin; Tangeritin |
Structure:
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Related Targets (Total: 8)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T54SZZ | Endoplasmic reticulum chaperone BiP | HSPA5 |
P11021 |
B | 1 Reference(s) |
| T75H3W | Cyclin-dependent kinase 2 | CDK2 |
P24941 |
B | 1 Reference(s) |
| T10S5F | Cyclin-dependent kinase 4 | CDK4 |
P11802 |
B | 1 Reference(s) |
| T64W2K | Cyclin-dependent kinase inhibitor 1 | CDKN1A |
P38936 |
B | 1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
C | 1 Reference(s) |
| T63BQU | Cytochrome P450 1A1 | CYP1A1 |
P04798 |
C | 1 Reference(s) |
| T02IOG | Cyclin-dependent kinase inhibitor 1B | CDKN1B |
P46527 |
C | 1 Reference(s) |
| T06MXL | Neprilysin | MME |
P08473 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 21)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0652 | Xiang Yuan Pi | 香橼皮 | Wilson citron | Citrus medica |
| H0088 | Ju He | 橘核 | Tangerine seed | Citrus reticulata |
| H0651 | Xiang Yuan | 香橼 | Wilson citron | Citrus medica |
| H0604 | Wu Wei Teng | 五味藤 | NA | Securidaca inappendiculata |
| H0602 | Wu Mei Rou | 乌梅肉 | Ebony | Prunus mume |
| H0084 | Jiu Li Xiang | 九里香 | Common jasminorange | Murraya paniculata |
| H1217 | Bai Mei Hua | 白梅花 | Japanese apricot flower | Prunus mume |
| H0052 | Jin Ju | 金橘 | Oval kumquat | Fortunella margarita |
| H0479 | Shu Qu Cao | 鼠曲草 | Cudweed | Gnaphalium affine |
| H0976 | Di Qing Pi | 地青皮 | NA | Pericarpium citri reticulatae viride |
| H0719 | Chen Pi | 陈皮 | Dried tangerine peel | Pericarpium citri reticulatae |
| H0347 | Qing Pi | 青皮 | Green tangerine peel | Pericarpium citri reticulatae viride |
| H0667 | Xiao Qing Pi | 小青皮 | Green tangerine peel | Pericarpium citri reticulatae viride |
| H0802 | Zhi Geng | 枳梗 | NA | Citrus aurantium |
| H0093 | Ju Pi | 橘皮 | Tangerine pericarp | Citrus reticulata |
| H0804 | Zhi Ke | 枳壳 | Seville ora nge unripe fruit | Citrus aurantium |
| H0046 | Jin Gan | 金柑 | Japanese kumquat | Fortunella japonica |
| H0601 | Wu Mei | 乌梅 | Japanese apricot | Prunus mume |
| H0805 | Zhi Ke Gan Jin Gao | 枳壳干浸膏 | Seville ora nge unripe fruit | Citrus aurantium |
| H0758 | Cheng Pi | 橙皮 | Bitter orange | Citrus aurantium |
| H0813 | Zhi Shi | 枳实 | Seville orange young fruit | Citrus aurantium |
Ckey description of the interaction between compound and target