Compound Description
| ID: C0541 | Common name: Neoechinulin A |
| IUPAC: (3S,6Z)-3-methyl-6-[[2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]methylidene]piperazine-2,5-dione | CAS: CAS:51551-29-2 |
| Chembl ID: CHEMBL400768 | Pubchem ID: CID:9996305 |
| Formula: C19H21N3O2 | TCM-ID: TCMC2703 |
| Smiles: C=CC(c1[nH]c2c(c1/C=C/1N=C(O)[C@@H](N=C1O)C)cccc2)(C)C | |
| Alias:
2,5-Piperazinedione, 3-[[2-(1,1-dimethyl-2-propenyl)-1H-indol-3-yl]methylene]-6-methyl-, (3Z,6S)-;
2,5-Piperazinedione, 3-[[2-(1,1-dimethyl-2-propenyl)-1H-indol-3-yl]methylene]-6-methyl-, [S-(Z)]-; (3Z,6S)-3-[[2-(1,1-Dimethyl-2-propen-1-yl)-1H-indol-3-yl]methylene]-6-methyl-2,5-piperazinedione; (-)-Neoechinulin A; Neoechinulin A; Neoechinuline A |
Structure:
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Related Targets (Total: 4)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T72J3R | Secretogranin-1 | CHGB |
P05060 |
B | 1 Reference(s) |
| T03YAI | Mitogen-activated protein kinase kinase kinase 5 | MAP3K5 |
Q99683 |
C | 1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
C | 1 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 7)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0691 | Xue Lian Hua | 雪莲花 | Snow lotus | Saussurea involucrata |
| H0159 | Ban Xia Qu | 半夏曲 | Pinellia tuber leaven | Pinellia ternata |
| H0690 | Xue Lian | 雪莲 | Snow lotus | Saussurea involucrata |
| H0155 | Ban Xia | 半夏 | Ternate pinellia | Pinellia ternata |
| H0439 | Sheng Ban Xia | 生半夏 | Ternate pinellia | Pinellia ternata |
| H0338 | Qing Ban Xia | 清半夏 | Ternate pinellia | Pinellia ternata |
| H0546 | Tian Shan Xue Lian Hua | 天山雪莲花 | NA | Saussurea involucrata |
Ckey description of the interaction between compound and target