HIT-result

ID: C0742	Common name: Crocin
IUPAC: bis[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl] (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioate	CAS: CAS:42553-65-1
Chembl ID: CHEMBL446785	Pubchem ID: CID:5281233
Formula: C44H64O24	TCM-ID: TCMC4310
Smiles: CC(=CC=CC=C(C)C=CC=C(C)C(=O)OC1C(C(C(C(O1)COC2C(C(C(C(O2)CO)O)O)O)O)O)O)C=CC=C(C)C(=O)OC3C(C(C(C(O3)COC4C(C(C(C(O4)CO)O)O)O)O)O)O
Alias: 8,8'-Diapo-ψ,ψ-carotenedioic acid, bis(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl) ester; Crocin; Crocetin bis(gentiobiosyl) ester; Crocetin di(β-D-gentiobiosyl) ester; Crocetin di-β-gentiobiosyl ester; Crocetin digentiobioside; Crocin 1; Crocin 4; Crocin A; Crocin I; all-trans-Crocetin di-β-D-gentiobiosyl ester; trans-Crocetin di(β-D-gentiobiosyl) ester; trans-Crocin-1; α-Crocin	Structure:

Target id	Protein Name	Gene Symbol	Uniprot ID	Target Level	No.of Literature Evidence
T85U8U	Caspase-3	CASP3	P42574	A	1 Reference(s)
T75MO6	Tyrosine-protein kinase ABL1	ABL1	P00519	A	1 Reference(s)
T88KAD	Sphingomyelin phosphodiesterase 2	SMPD2	O60906	B	1 Reference(s)
T42EAZ	Vascular endothelial growth factor A	VEGFA	P15692	C	1 Reference(s)
T25NSJ	Mitogen-activated protein kinase 3	MAPK3	P27361	C	1 Reference(s)
T79WXA	Mitogen-activated protein kinase 1	MAPK1	P28482	C	2 Reference(s)
T10ICM	Oxidized low-density lipoprotein receptor 1	OLR1	P78380	C	1 Reference(s)
T33OPP	Interleukin-6	IL6	P05231	C	1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0818	Zhi Zi	栀子	Cape jasmine fruit	Gardenia jasminoides

Compound Description

Related Targets (Total: 8)

Related Herbs (Total: 1)