Target Description
| Type | Detail |
|---|---|
| Target ID | T88KAD |
| Protein Name | Sphingomyelin phosphodiesterase 2 |
| Uniprot ID |
O60906 |
| Protein Name Alias | EC 3.1.4.12; Lyso-platelet-activating factor-phospholipase C; Lyso-PAF-PLC; Neutral sphingomyelinase; N-SMase; nSMase; nSMase1 |
| Gene ID |
6610 |
| Gene Symbol | SMPD2 |
| Gene Alias | NA |
| TTD | T57316: Research target |
| Pfam | PF03372 |
| GO |
0009612:response to mechanical stimulus
0006684:sphingomyelin metabolic process 0030149:sphingolipid catabolic process 0035556:intracellular signal transduction 0006685:sphingomyelin catabolic process 0046872:metal ion binding 0005887:integral component of plasma membrane 0005783:endoplasmic reticulum 0005901:caveola 0004620:phospholipase activity 0004767:sphingomyelin phosphodiesterase activity 0016020:membrane 0071944:cell periphery 0006687:glycosphingolipid metabolic process 0046513:ceramide biosynthetic process 0005886:plasma membrane 2000304:positive regulation of ceramide biosynthetic process |
| PDB | NA |
| Drugbank | NA |
| KEGG | hsa:6610 |
