| ID: C0192 | Common name: Lipoic Acid | 
| IUPAC: 5-[(3R)-dithiolan-3-yl]pentanoic acid | CAS: CAS:1200-22-2 | 
| Chembl ID: CHEMBL134342 | Pubchem ID: CID:6112 | 
| Formula: C8H14O2S2 | TCM-ID: TCMC1499 | 
| Smiles: C1CSSC1CCCCC(=O)O | |
| Alias: 
                        
                        1,2-Dithiolane-3-pentanoic acid, (R)-; 1,2-Dithiolane-3-valeric acid, (+)-; (3R)-1,2-Dithiolane-3-pentanoic acid; (R)-(+)-1,2-Dithiolane-3-pentanoic acid; (R)-(+)-α-Lipoic acid; (R)-5-(1,2-Dithiolan-3-yl)pentanoicacid; (R)-Lipoic acid; (R)-α-Lipoic acid; Berlition; Byodinoral 300; Destior-R; Lipoec; Lipoic acid; Matris thioctic; R-(+)-Thioctic acid; Thioderm; Thiogamma; Tiobec; Tiobec Retard; alpha-Lipoic acid; d-Thioctic acid; α-(+)-Lipoic acid; α-Lipoic acid | Structure:   | 
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence | 
|---|---|---|---|---|---|
| T32OC4 | Aldehyde dehydrogenase, mitochondrial | ALDH2 | P05091 | A | 2 Reference(s) | 
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 | P19838 | A | 1 Reference(s) | 
| T16BEL | [Pyruvate dehydrogenase | PDK4 | Q16654 | A | 1 Reference(s) | 
| T58XLK | Tyrosine-protein phosphatase non-receptor type 1 | PTPN1 | P18031 | B | 1 Reference(s) | 
| T16A2X | Catalase | CAT | P04040 | B | 1 Reference(s) | 
| T06QUL | Fractalkine | CX3CL1 | P78423 | B | 1 Reference(s) | 
| T58K62 | Frataxin, mitochondrial | FXN | Q16595 | B | 1 Reference(s) | 
| T13KGH | Tyrosinase | TYR | P14679 | B | 1 Reference(s) | 
| T23P74 | Caspase-9 | CASP9 | P55211 | B | 1 Reference(s) | 
| T88KAD | Sphingomyelin phosphodiesterase 2 | SMPD2 | O60906 | B | 1 Reference(s) | 
| T93WZG | G1/S-specific cyclin-D1 | CCND1 | P24385 | B | 1 Reference(s) | 
| T86ROZ | Heme oxygenase 1 | HMOX1 | P09601 | B | 2 Reference(s) | 
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 | P10415 | B | 1 Reference(s) | 
| T83YZD | Acetylcholinesterase | ACHE | P22303 | B | 1 Reference(s) | 
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG | P37231 | B | 2 Reference(s) | 
| T89L4V | Insulin | INS | P01308 | B | 1 Reference(s) | 
| T09AAD | NADPH--cytochrome P450 reductase | POR | P16435 | B | 1 Reference(s) | 
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 | Q16236 | B | 1 Reference(s) | 
| T83QQX | Cytochrome b-245 light chain | CYBA | P13498 | B | 1 Reference(s) | 
| T00H7Q | Neutrophil cytosol factor 1 | NCF1 | P14598 | B | 1 Reference(s) | 
| T33OPP | Interleukin-6 | IL6 | P05231 | B | 1 Reference(s) | 
| T09H2Z | Nitric oxide synthase, inducible | NOS2 | P35228 | B | 1 Reference(s) | 
| T59IKQ | Vascular cell adhesion protein 1 | VCAM1 | P19320 | B | 1 Reference(s) | 
| T23VMI | Tumor necrosis factor | TNF | P01375 | C | 1 Reference(s) | 
| T43SM9 | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | PPARGC1A | Q9UBK2 | C | 1 Reference(s) | 
| T70SFS | Superoxide dismutase [Mn], mitochondrial | SOD2 | P04179 | C | 1 Reference(s) | 
| T90XYZ | C-reactive protein | CRP | P02741 | C | 2 Reference(s) | 
| T10RDU | Patatin-like phospholipase domain-containing protein 2 | PNPLA2 | Q96AD5 | C | 1 Reference(s) |