ID: C0192 | Common name: Lipoic Acid |
IUPAC: 5-[(3R)-dithiolan-3-yl]pentanoic acid | CAS: CAS:1200-22-2 |
Chembl ID: CHEMBL134342 | Pubchem ID: CID:6112 |
Formula: C8H14O2S2 | TCM-ID: TCMC1499 |
Smiles: C1CSSC1CCCCC(=O)O | |
Alias:
1,2-Dithiolane-3-pentanoic acid, (R)-;
1,2-Dithiolane-3-valeric acid, (+)-; (3R)-1,2-Dithiolane-3-pentanoic acid; (R)-(+)-1,2-Dithiolane-3-pentanoic acid; (R)-(+)-α-Lipoic acid; (R)-5-(1,2-Dithiolan-3-yl)pentanoicacid; (R)-Lipoic acid; (R)-α-Lipoic acid; Berlition; Byodinoral 300; Destior-R; Lipoec; Lipoic acid; Matris thioctic; R-(+)-Thioctic acid; Thioderm; Thiogamma; Tiobec; Tiobec Retard; alpha-Lipoic acid; d-Thioctic acid; α-(+)-Lipoic acid; α-Lipoic acid |
Structure:
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Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
---|---|---|---|---|---|
T32OC4 | Aldehyde dehydrogenase, mitochondrial | ALDH2 |
P05091 |
A | 2 Reference(s) |
T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
A | 1 Reference(s) |
T16BEL | [Pyruvate dehydrogenase | PDK4 |
Q16654 |
A | 1 Reference(s) |
T58XLK | Tyrosine-protein phosphatase non-receptor type 1 | PTPN1 |
P18031 |
B | 1 Reference(s) |
T16A2X | Catalase | CAT |
P04040 |
B | 1 Reference(s) |
T06QUL | Fractalkine | CX3CL1 |
P78423 |
B | 1 Reference(s) |
T58K62 | Frataxin, mitochondrial | FXN |
Q16595 |
B | 1 Reference(s) |
T13KGH | Tyrosinase | TYR |
P14679 |
B | 1 Reference(s) |
T23P74 | Caspase-9 | CASP9 |
P55211 |
B | 1 Reference(s) |
T88KAD | Sphingomyelin phosphodiesterase 2 | SMPD2 |
O60906 |
B | 1 Reference(s) |
T93WZG | G1/S-specific cyclin-D1 | CCND1 |
P24385 |
B | 1 Reference(s) |
T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
B | 2 Reference(s) |
T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
B | 1 Reference(s) |
T83YZD | Acetylcholinesterase | ACHE |
P22303 |
B | 1 Reference(s) |
T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
B | 2 Reference(s) |
T89L4V | Insulin | INS |
P01308 |
B | 1 Reference(s) |
T09AAD | NADPH--cytochrome P450 reductase | POR |
P16435 |
B | 1 Reference(s) |
T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
B | 1 Reference(s) |
T83QQX | Cytochrome b-245 light chain | CYBA |
P13498 |
B | 1 Reference(s) |
T00H7Q | Neutrophil cytosol factor 1 | NCF1 |
P14598 |
B | 1 Reference(s) |
T33OPP | Interleukin-6 | IL6 |
P05231 |
B | 1 Reference(s) |
T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
B | 1 Reference(s) |
T59IKQ | Vascular cell adhesion protein 1 | VCAM1 |
P19320 |
B | 1 Reference(s) |
T23VMI | Tumor necrosis factor | TNF |
P01375 |
C | 1 Reference(s) |
T43SM9 | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | PPARGC1A |
Q9UBK2 |
C | 1 Reference(s) |
T70SFS | Superoxide dismutase [Mn], mitochondrial | SOD2 |
P04179 |
C | 1 Reference(s) |
T90XYZ | C-reactive protein | CRP |
P02741 |
C | 2 Reference(s) |
T10RDU | Patatin-like phospholipase domain-containing protein 2 | PNPLA2 |
Q96AD5 |
C | 1 Reference(s) |