Target Description

Type Detail
Target ID T16BEL
Protein Name [Pyruvate dehydrogenase
Uniprot ID Q16654
Protein Name Alias acetyl-transferring;  EC 2.7.11.2;  Pyruvate dehydrogenase kinase isoform 4
Gene ID 5166
Gene Symbol PDK4
Gene Alias PDHK4
TTD NA
Pfam PF02518 ; PF10436
GO
0010906:regulation of glucose metabolic process

0042304:regulation of fatty acid biosynthetic process

0004672:protein kinase activity

0010565:regulation of cellular ketone metabolic process

0071398:cellular response to fatty acid

0004740:pyruvate dehydrogenase (acetyl-transferring) kinase activity

0006885:regulation of pH

0005524:ATP binding

0006006:glucose metabolic process

0010510:regulation of acetyl-CoA biosynthetic process from pyruvate

0046320:regulation of fatty acid oxidation

0008286:insulin receptor signaling pathway

0006468:protein phosphorylation

2000811:negative regulation of anoikis

0005759:mitochondrial matrix

0005739:mitochondrion

0045124:regulation of bone resorption

0072593:reactive oxygen species metabolic process

0042593:glucose homeostasis

0042594:response to starvation

0009267:cellular response to starvation

PDB 3D2R ; 2E0A ; 2ZKJ ; 2ZDY ; 2ZDX
Drugbank DB08356 ; DB00755
KEGG hsa:5166

Related Compounds  (Total: 2)

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C0192
Name: Lipoic Acid
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C0600
Name: Adenosine


Related Herbs  (Total: 3)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0938 Da Suan大蒜 GarlicAllium sativum
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens