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Target Description
Type
Detail
Target ID
T16BEL
Protein Name
[Pyruvate dehydrogenase
Uniprot ID
Q16654
Protein Name Alias
acetyl-transferring; EC 2.7.11.2; Pyruvate dehydrogenase kinase isoform 4
Gene ID
5166
Gene Symbol
PDK4
Gene Alias
PDHK4
TTD
NA
Pfam
PF02518
;
PF10436
GO
0010906:regulation of glucose metabolic process
0042304:regulation of fatty acid biosynthetic process
0004672:protein kinase activity
0010565:regulation of cellular ketone metabolic process
0071398:cellular response to fatty acid
0004740:pyruvate dehydrogenase (acetyl-transferring) kinase activity
0006885:regulation of pH
0005524:ATP binding
0006006:glucose metabolic process
0010510:regulation of acetyl-CoA biosynthetic process from pyruvate
0046320:regulation of fatty acid oxidation
0008286:insulin receptor signaling pathway
0006468:protein phosphorylation
2000811:negative regulation of anoikis
0005759:mitochondrial matrix
0005739:mitochondrion
0045124:regulation of bone resorption
0072593:reactive oxygen species metabolic process
0042593:glucose homeostasis
0042594:response to starvation
0009267:cellular response to starvation
PDB
3D2R
;
2E0A
;
2ZKJ
;
2ZDY
;
2ZDX
Drugbank
DB08356
;
DB00755
KEGG
hsa:5166
Related Compounds (Total: 2)
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C0192
Name: Lipoic Acid
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C0600
Name: Adenosine
Related Herbs (Total: 3)
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Herb id
Chinese Pin Yin
Chinese Character
English Name
Latin Name
H0847
Zi He Che
紫河车
Human placenta
Homo sapiens
H0938
Da Suan
大蒜
Garlic
Allium sativum
H0360
Ren Zhong Bai
人中白
Human urine sediment
Homo sapiens