Target Description

Type Detail
Target ID T83QQX
Protein Name Cytochrome b-245 light chain
Uniprot ID P13498
Protein Name Alias Cytochrome b(558) alpha chain;  Cytochrome b558 subunit alpha;  Neutrophil cytochrome b 22 kDa polypeptide;  Superoxide-generating NADPH oxidase light chain subunit;  p22 phagocyte B-cytochrome;  p22-phox;  p22phox
Gene ID 1535
Gene Symbol CYBA
Gene Alias NA
TTD NA
Pfam PF05038
GO
0043020:NADPH oxidase complex

0014895:smooth muscle hypertrophy

0046872:metal ion binding

0006801:superoxide metabolic process

0016020:membrane

0035579:specific granule membrane

0030670:phagocytic vesicle membrane

0030141:secretory granule

0032755:positive regulation of interleukin-6 production

0006954:inflammatory response

0009055:electron transfer activity

0046982:protein heterodimerization activity

1903428:positive regulation of reactive oxygen species biosynthetic process

0045454:cell redox homeostasis

0070821:tertiary granule membrane

0005789:endoplasmic reticulum membrane

0002479:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

0042554:superoxide anion generation

0043312:neutrophil degranulation

0032760:positive regulation of tumor necrosis factor production

0045087:innate immune response

0031343:positive regulation of cell killing

0034137:positive regulation of toll-like receptor 2 signaling pathway

0005886:plasma membrane

0050766:positive regulation of phagocytosis

0045730:respiratory burst

0034599:cellular response to oxidative stress

0050665:hydrogen peroxide biosynthetic process

0048010:vascular endothelial growth factor receptor signaling pathway

0017124:SH3 domain binding

0020037:heme binding

1900426:positive regulation of defense response to bacterium

0017004:cytochrome complex assembly

PDB 1WLP
Drugbank DB00514
KEGG hsa:1535

Related Compounds  (Total: 3)

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C0192
Name: Lipoic Acid
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C0916
Name: Apocynin
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C1211
Name: Cannabidiol


Related Herbs  (Total: 13)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1202 Hu Huang Lian胡黄连 PicrorhizaPicrorhiza kurrooa
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0049 Bai Wei白薇 Blackend swallowwortCynanchum atratum
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H0007 Huo Xue Teng活血藤 NASargentodoxa cuneata
H0348 Qing Wa Qi青蛙七 Wall irisIris tectorum
H0270 Mu Hu Die木蝴蝶 Indian trumpetflowerOroxylum indicum
H0995 Dong Chong Xia Cao冬虫夏草 AwetoCordyceps sinensis
H0253 Mian Hua Gen棉花根 Levant cotton rootGossypium herbaceum
H0003 Huo Ma Ren火麻仁 Hemp fimble seedCannabis sativa
H0204 Ma Ren麻仁 NACannabis sativa
H0939 Da Xue Teng大血藤 SargentgloryvineSargentodoxa cuneata
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens