Compound Description
| ID: C0916 | Common name: Apocynin |
| IUPAC: 1-(4-hydroxy-3-methoxyphenyl)ethanone | CAS: CAS:498-02-2 |
| Chembl ID: CHEMBL346919 | Pubchem ID: CID:2214 |
| Formula: C9H10O3 | TCM-ID: TCMC714 |
| Smiles: COc1cc(ccc1O)C(=O)C | |
| Alias:
Acetophenone, 4'-hydroxy-3'-methoxy-;
1-(4-Hydroxy-3-methoxyphenyl)ethanone; 1-(4-Hydroxy-3-methoxyphenyl)ethan-1-one; 2-Methoxy-4-acetylphenol; 3-Methoxy-4-hydroxyphenylethanone; 3'-Methoxy-4'-hydroxyacetophenone; 4-Acetyl-1-hydroxy-2-methoxybenzene; 4-Acetyl-2-methoxyphenol; 4-Acetylguaiacol; 4-Hydroxy-3-methoxyphenyl methyl ketone; 4'-Hydroxy-3'-methoxyacetophenone; Acetoguaiacol; Acetoguaiacon; Acetoguaiacone; Acetoguaicone; Acetovanillone; Apocynin; Apocynine; NSC 209524; NSC 2146 |
Structure:
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Related Targets (Total: 12)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T80OPZ | NADPH oxidase 4 | NOX4 |
Q9NPH5 |
A | 2 Reference(s) |
| T20TB8 | NADPH oxidase 1 | NOX1 |
Q9Y5S8 |
A | 24 Reference(s) |
| T20E5P | Cytochrome b-245 heavy chain | CYBB |
P04839 |
A | 5 Reference(s) |
| T20HY9 | 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial | DECR1 |
Q16698 |
A | 1 Reference(s) |
| T00H7Q | Neutrophil cytosol factor 1 | NCF1 |
P14598 |
A | 1 Reference(s) |
| T68R23 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | PCK2 |
Q16822 |
A | 1 Reference(s) |
| T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
A | 1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
A | 1 Reference(s) |
| T53QS9 | Glutamate--cysteine ligase catalytic subunit | GCLC |
P48506 |
C | 1 Reference(s) |
| T83QQX | Cytochrome b-245 light chain | CYBA |
P13498 |
C | 1 Reference(s) |
| T91OUC | Mucin-5AC | MUC5AC |
P98088 |
C | 1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 9)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1202 | Hu Huang Lian | 胡黄连 | Picrorhiza | Picrorhiza kurrooa |
| H0049 | Bai Wei | 白薇 | Blackend swallowwort | Cynanchum atratum |
| H0446 | Sheng Jiang | 生姜 | Fresh common ginger | Zingiber officinale |
| H0007 | Huo Xue Teng | 活血藤 | NA | Sargentodoxa cuneata |
| H0348 | Qing Wa Qi | 青蛙七 | Wall iris | Iris tectorum |
| H0270 | Mu Hu Die | 木蝴蝶 | Indian trumpetflower | Oroxylum indicum |
| H0995 | Dong Chong Xia Cao | 冬虫夏草 | Aweto | Cordyceps sinensis |
| H0253 | Mian Hua Gen | 棉花根 | Levant cotton root | Gossypium herbaceum |
| H0939 | Da Xue Teng | 大血藤 | Sargentgloryvine | Sargentodoxa cuneata |
Ckey description of the interaction between compound and target