Compound Description
| ID: C0921 | Common name: Aristolochic Acid |
| IUPAC: NA | CAS: CAS:313-67-7 |
| Chembl ID: CHEMBL93353 | Pubchem ID: CID:2236 |
| Formula: C17H11NO7 | TCM-ID: TCMC722 |
| Smiles: COc1cccc2c1cc(N(=O)=O)c1c2c2OCOc2cc1C(=O)O | |
| Alias:
8-Methoxy-6-nitrophenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid;
8-Methoxy-3,4-methylenedioxy-10-nitrophenanthrene-1-carboxylic acid; Aristolochia A; Aristolochic acid; Aristolochic acid 1; Aristolochic acid A; Aristolochic acid I; NSC 11926; NSC 50413; TR 1736; Tardolyt |
Structure:
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Related Targets (Total: 4)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T40LTN | Phospholipase A2, membrane associated | PLA2G2A |
P14555 |
A | 1 Reference(s) |
| T30TYH | Phospholipase A2 | PLA2G1B |
P04054 |
A | 9 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
B | 1 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 10)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1119 | Guang Fang Ji | 广防己 | Fangchi | Aristolochia fangchi |
| H1116 | Guan Mu Tong | 关木通 | Manchurian dutchmanspipe | Aristolochia manshuriensis |
| H0196 | Ma Dou Ling | 马兜铃 | Slender dutchmanspipe | Aristolochia debilis |
| H0833 | Zhu Sha Lian | 朱砂莲 | Kaempfer dutchmanspipe | Aristolochia kaempferi |
| H0629 | Xi Xin | 细辛 | Siebold wildginger | Asarum sieboldii |
| H1155 | Han Fang Ji | 汉防己 | Yellowmouth dutchmanspipe | Sinomenium acutum |
| H1033 | Fang Ji | 防己 | Fourstamen stephania | Stephania tetrandra |
| H0346 | Qing Mu Xiang | 青木香 | Slender dutchmanspipe root | Aristolochia debilis |
| H0341 | Qing Feng Teng | 青风藤 | Orientvine | Sinomenium acutum |
| H0273 | Mu Tong | 木通 | Fiveleaf akebia | Akebia quinata |
Ckey description of the interaction between compound and target