Herb Description
| Herb ID: H1116 | Chinese Character: 关木通 |
| English Name: Manchurian dutchmanspipe | Latin Name: Aristolochia manshuriensis |
| Chinese Pin Yin : Guan Mu Tong | TCM-ID: TCMH718 |
| Therapeutic Function in Chinese : 利水渗湿 | Therapeutic Function in English: For promoting diuresis and penetrating dampness |
| Herb Function: Remove heat from the heart, relieve dysuria and promote diuresis, stimulate menstrual discharge, and promote the flow of milk | |
Related Targets (Total: 33)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T40LTN | Phospholipase A2, membrane associated | PLA2G2A |
P14555 |
1 Reference(s) |
| T30TYH | Phospholipase A2 | PLA2G1B |
P04054 |
9 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
2 Reference(s) |
| T25Y64 | Cholinesterase | BCHE |
P06276 |
1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
1 Reference(s) |
| T81I4T | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | PRKAA1 |
Q13131 |
1 Reference(s) |
| T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
1 Reference(s) |
| T13KGH | Tyrosinase | TYR |
P14679 |
1 Reference(s) |
| T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
1 Reference(s) |
| T58XLK | Tyrosine-protein phosphatase non-receptor type 1 | PTPN1 |
P18031 |
1 Reference(s) |
| T26EZU | Myc proto-oncogene protein | MYC |
P01106 |
1 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
1 Reference(s) |
| T32UNL | Lens fiber major intrinsic protein | MIP |
P30301 |
1 Reference(s) |
| T64UH1 | Nitric oxide synthase, endothelial | NOS3 |
P29474 |
1 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
1 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
1 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
1 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
1 Reference(s) |
| T60UPF | Parvalbumin alpha | PVALB |
P20472 |
2 Reference(s) |
| T69RXK | Cytochrome P450 2C9 | CYP2C9 |
P11712 |
1 Reference(s) |
| T18CUI | Neuron-specific calcium-binding protein hippocalcin | HPCA |
P84074 |
1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
1 Reference(s) |
| T54CIF | Interleukin-8 | CXCL8 |
P10145 |
1 Reference(s) |
| T09BRP | NA | PKB_RS07820 |
NA |
1 Reference(s) |
| T39RV3 | Dual specificity mitogen-activated protein kinase kinase 1 | MAP2K1 |
Q02750 |
1 Reference(s) |
| T66S13 | Dual specificity mitogen-activated protein kinase kinase 2 | MAP2K2 |
P36507 |
1 Reference(s) |
| T08SJX | Astrocytic phosphoprotein PEA-15 | PEA15 |
Q15121 |
1 Reference(s) |
| T38OQ4 | Peroxiredoxin-2 | PRDX2 |
P32119 |
1 Reference(s) |
| T38J3Y | Gamma-enolase | ENO2 |
P09104 |
1 Reference(s) |
| T82I7J | C-C motif chemokine 16 | CCL16 |
O15467 |
1 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
1 Reference(s) |
| T38EQ6 | NAD(P)H dehydrogenase [quinone] 1 | NQO1 |
P15559 |
1 Reference(s) |
Related Compounds (Total: 5)
C0921
Name: Aristolochic Acid
C0291
Name: Paraben
C0073
Name: Ferulic Acid
C1258
Name: Coumaric Acid
C0262
Name: Oleanolic_Acid
key description of the interaction between compound and target