Compound Description
| ID: C0262 | Common name: Oleanolic_Acid |
| IUPAC: (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid | CAS: NA |
| Chembl ID: CHEMBL168 | Pubchem ID: CID:10494 |
| Formula: C30H48O3 | TCM-ID: TCMC1786 |
| Smiles: CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C(=O)O)C | |
| Alias:
NA
|
Structure:
|
Related Targets (Total: 5)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
B | 1 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
B | 1 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
B | 1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
C | 1 Reference(s) |
| T38EQ6 | NAD(P)H dehydrogenase [quinone] 1 | NQO1 |
P15559 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 135)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0004 | Huo Xiang | 藿香 | Patchouli | Pogostemon cablin |
| H0713 | Che Qian Cao | 车前草 | all-grass of rippleseed plantain | Plantago depressa |
| H1127 | Guang Shan Zha | 广山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H0308 | Pi Ba Ren | 枇杷仁 | NA | Eriobotrya japonica |
| H0698 | Ya Zao | 牙皂 | Chinese honeylocust abnormal fruit | Gleditsia sinensis |
| H0779 | Zao Jiao Zhen | 皂角针 | Chinese honeylocust spine | Gleditsia sinensis |
| H0626 | Xi Nan Huang Qin | 西南黄芩 | Yunnan skullcap | Scutellaria amoena |
| H0211 | Mai Dong Men | 麦冬门 | Dwarf lilyturf | Ophiopogon japonicus |
| H0357 | Ren Shen | 人参 | Ginseng | Panax ginseng |
| H0002 | Hui Xiang | 茴香 | Fennel fruit | Foeniculum vulgare |
| H0074 | Jing Jie Tan | 荆芥炭 | NA | Schizonepetae herba |
| H0336 | Qin Jiao | 秦艽 | large-leaved gentian | Gentiana macrophylla |
| H0854 | Zi Wei Gen Pi | 紫葳根皮 | NA | Campsis grandiflora |
| H0639 | Xiang Cha Cai | 香茶菜 | Common rabdosia | Isodon amethystoides |
| H1109 | Bai Hua She She Cao | 白花蛇舌草 | Spreading hedyitis | Oldenlandia diffusa |
| H0419 | Shan Zha | 山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H1072 | Gan Cao Gao | 甘草膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0912 | Ci Wu Jia Jin Yu | 刺五加浸育 | Manypr ickle acanthopana x | Eleutherococcus senticosus |
| H1049 | Feng Xiang Zhi Chou Gao | 枫香脂稠膏 | NA | Liquidambar formosana |
| H1010 | Du Huo Xiang | 杜藿香 | Patchouli | Pogostemon cablin |
| H0177 | Lu Lu Tong | 路路通 | Beautiful sweetgum | Liquidambar formosana |
| H0637 | Cha Ye | 茶叶 | Common tea | Camellia sinensis |
| H1075 | Gan Cao Liu Jin Gao | 甘草流浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0989 | Ding Kui Cao | 丁葵草 | Herb of twinleaf zornia | Kummerowia striata |
| H0036 | Jie Geng | 桔梗 | Balloonflower | Platycodon grandiflorum |
| H1073 | Gan Cao Jie | 甘草节 | Glycyrrhiza uralensis fisch | Glycyrrhiza uralensis |
| H1047 | Feng Xiang Ye | 枫香叶 | NA | Liquidambar formosana |
| H0570 | Tu Fu Ling | 土茯苓 | Glabrous greenbrier | Smilax glabra |
| H1138 | Bai Jiang Cao | 败酱草 | All - grass of dahurian patrinia | Thlaspi arvense |
| H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
| H0391 | Sang Pi | 桑皮 | Prepared root-bark white mulberry | Morus alba |
| H0300 | Nv Zhen Zi | 女贞子 | Glossy privet fruit | Ligustrum lucidum |
| H0638 | Xiang Bei | 象贝 | Fritillaria | Fritillaria thunbergii |
| H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
| H0591 | Wei Ling Cai | 委陵菜 | Chinese cinquefoil | Potentilla chinensis |
| H0219 | Man Shan Hong | 满山红 | Dahurian rhododendron | Rhododendron dauricum |
| H0380 | San Qi Gan Jin Gao | 三七干浸膏 | Sanchi | Panax notoginseng |
| H0470 | Shi Ye | 柿叶 | Persimmon leaf | Diospyros kaki |
| H0396 | Sang Ye | 桑叶 | White mulberry leaf | Morus alba |
| H0038 | Jie Geng Gan Gao Fen | 桔梗干膏粉 | Balloonflower | Platycodon grandiflorum |
| H1070 | Gan Cao Gan Gao Fen | 甘草干膏粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0747 | An Xi Xiang | 安息香 | Sumatra snowbel | Styrax benzoin |
| H0040 | Jie Geng Liu Zhu Gao | 桔梗流注膏 | Balloonflower | Platycodon grandiflorum |
| H0572 | Tu Huo Xiang | 土藿香 | Patchouli | Pogostemon cablin |
| H0420 | Shan Zha Chou Gao | 山楂稠膏 | Chinese hawthorn | Crataegus pinnatifida |
| H0037 | Jie Geng Gan Gao | 桔梗干膏 | Balloonflower | Platycodon grandiflorum |
| H0069 | Jin Ying Zi Ti Qu Ye | 金樱子提取液 | Cherokee rose seed | Rosa laevigata |
| H0951 | Dan Shen Jin Gao | 丹参浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H1097 | Gong Ding Xiang | 公丁香 | NA | Syzygium aromaticum |
| H0229 | Mao Da Ding Cao | 毛大丁草 | Pilose gerbera | Gerbera piloselloides |
| H0226 | Man Yue Mei | 蔓越莓 | Cranberry | Vaccinium oxycoccos |
| H0913 | Ci Wu Jia Qing Gao | 刺五加清膏 | Manypr ickle acanthopana x | Eleutherococcus senticosus |
| H0210 | Mai Dong | 麦冬 | Liriope | Ophiopogon japonicus |
| H0290 | Niu Er Feng | 牛耳枫 | calyx-shaped daphniphyllum fruit | Daphniphyllum calycinum |
| H0060 | Jin Si Ku Lian | 金丝苦楝 | NA | Cardiospermum halicacabum |
| H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
| H0875 | Chuan Mu Tong | 川木通 | Armand clematis stem | Clematidis armandii caulis |
| H1067 | Gan Cao Fen | 甘草粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0384 | San Qi Ye | 三七叶 | Folium panax notoginseng | Panax notoginseng |
| H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
| H0909 | Ci Wu Jia Gao | 刺五加膏 | Manypr ickle acanthopana x | Eleutherococcus senticosus |
| H0193 | Ma Bian Cao | 马鞭草 | European verbena | Verbena officinalis |
| H0067 | Jin Ying Zi | 金樱子 | Cherokee rose seed | Rosa laevigata |
| H0871 | Chuan Duan | 川断 | Teasels | Dipsacus asper |
| H0427 | Shan Zhu Yu | 山茱萸 | Asiatic cornelian cherry | Cornus officinalis |
| H0365 | Rou Dou Kou | 肉豆蔻 | Common nutmeg | Myristica fragrans |
| H0152 | Ling Zhi Jin Gao | 灵芝浸膏 | NA | Ganoderma lucidum |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0949 | Dan Shen | 丹参 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0422 | Shan Zha Tan | 山楂炭 | Chinese hawthorn | Crataegus pinnatifida |
| H0932 | Ba Qia | 菝葜 | Chinaroot greenbrier | Smilax china |
| H1186 | Hong Gen Cao | 红根草 | Hispid sage | Salvia prionitis |
| H0614 | Wu Zhao Long | 五爪龙 | Cairo morningglory | Ipomoea cairica |
| H0848 | Zi Jin Niu | 紫金牛 | Japanese ardisia | Ardisia japonica |
| H1203 | Hu Ji Sheng | 槲寄生 | Colored mistletoe | Viscum coloratum |
| H0715 | Che Qian Zi | 车前子 | seed of asiatic pantain | Plantago asiatica |
| H0020 | Ji Yan Cao | 鸡眼草 | Striate kummerowia | Kummerowia striata |
| H0212 | Mai Dong Rou | 麦冬肉 | Dwarf lilyturf | Ophiopogon japonicus |
| H0385 | San Qi Ye Jing | 三七叶茎 | Sanchi | Panax notoginseng |
| H1074 | Gan Cao Jin Gao | 甘草浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0085 | Jiu Yu Rou | 酒萸肉 | Asiatic cornelian cherry | Cornus officinalis |
| H1184 | Bai Lian | 白蔹 | Japanese ampelopsis | Ampelopsis japonica |
| H0908 | Ci Wu Jia | 刺五加 | Manypr ickle acanthopana x | Eleutherococcus senticosus |
| H0279 | Nan Gua | 南瓜 | Cushaw | Cucurbita moschata |
| H1069 | Gan Cao Gan Gao | 甘草干膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |
| H0702 | Yan Bai Cai | 岩白菜 | Purple bergenia | Bergenia purpurascens |
| H0039 | Jie Geng Liu Jin Gao | 桔梗流浸膏 | Balloonflower | Platycodon grandiflorum |
| H0632 | Xia Ku Cao | 夏枯草 | Common selfheal | Prunella vulgaris |
| H0990 | Ding Xiang | 丁香 | Clove tree | Syzygium aromaticum |
| H0361 | Ren Zi Cao | 人字草 | Herb of twinleaf zornia | Kummerowia striata |
| H0358 | Ren Shen Ye | 人参叶 | Ginseng leaf | Panax ginseng |
| H0421 | Shan Zha Qing Gao | 山楂清膏 | Chinese hawthorn | Crataegus pinnatifida |
| H0524 | Tan Xiang | 檀香 | Sandalwood | Santalum album |
| H0297 | Niu Xi | 牛膝 | Twotooth achyranthes | Achyranthes bidentata |
| H0453 | Shi Di | 柿蒂 | Persimmon persistent calyx | Diospyros kaki |
| H1116 | Guan Mu Tong | 关木通 | Manchurian dutchmanspipe | Aristolochia manshuriensis |
| H0382 | San Qi Hua | 三七花 | Sanchi | Panax notoginseng |
| H0801 | Chong Bai La | 虫白蜡 | Cera chinensis wax | Ericerus pela |
| H0383 | San Qi Jing Ye | 三七茎叶 | Sanchi | Panax notoginseng |
| H0950 | Dan Shen Gan Jin Gao | 丹参干浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0337 | Qin Jiao Hua | 秦艽花 | large-leaved gentian flower | Gentiana straminea |
| H0240 | Mi Gan Cao | 蜜甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1120 | Guang Huo Xiang | 广藿香 | Patchouli | Pogostemon cablin |
| H0381 | San Qi Gao Fen | 三七膏粉 | Sanchi | Panax notoginseng |
| H0777 | Zao Jia | 皂荚 | Chinese honeylocust | Gleditsia sinensis |
| H0379 | Bian Xu | 萹蓄 | Common knotgrass | Polygonum aviculare |
| H1066 | Gan Cao | 甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0733 | Ye Shan Zha | 野山楂 | nippon bawthorn | Crataegus pinnatifida |
| H0496 | Shui Ze Lan | 水泽兰 | NA | Lycopus lucidus |
| H0894 | Chuan Xu Duan | 川续断 | Himalayan teasel | Dipsacus asperoides |
| H0068 | Jin Ying Zi Rou | 金樱子肉 | Cherokee rose seed | Rosa laevigata |
| H1004 | Bai Cha | 白茶 | White tea | Camellia sinensis |
| H0035 | Bai Su Zi | 白苏子 | Common perilla fruit | Perilla frutescens |
| H0555 | Tie Xian Cai | 铁苋菜 | Copperleaf herb | Herba acalyphae |
| H0139 | Lian Qiao | 连翘 | Weeping forsythia | Forsythia suspensa |
| H0273 | Mu Tong | 木通 | Fiveleaf akebia | Akebia quinata |
| H0397 | Sang Zhi | 桑枝 | White mulberry branch | Morus alba |
| H1211 | Bai Mei | 白眉 | pilose gerbera herb | Gerbera piloselloides |
| H0296 | Niu Teng | 牛藤 | twotooth achyranthes root | Achyranthes bidentata |
| H0444 | Sheng Gan Cao | 生甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0153 | Ling Zhi(1) | 灵芝 | Lucid ganoderma | Ganoderma lucidum |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0844 | Zi Cao | 紫草 | Redroot gromwell | Lithospermum erythrorhizon |
| H0349 | Qing Ye Dan | 青叶胆 | Mileen swertia | Swertia mileensis |
| H0617 | Qian Cao Teng | 茜草藤 | NA | Rubia cordifolia |
| H1117 | Guan Zhong | 贯众 | Male fern rhizome | Dryopteris crassirhizoma |
| H0320 | Qi Shu Gen | 漆树根 | true lacquertree root | Toxicodendron succedaneum |
| H0571 | Tu Gan Cao | 土甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0910 | Ci Wu Jia Jin Gao | 刺五加浸膏 | Manypr ickle acanthopana x | Eleutherococcus senticosus |
| H1071 | Gan Cao Gan Jin Gao | 甘草干浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0416 | Shan Shen | 山参 | NA | Panax ginseng |
| H0213 | Mai Men Dong | 麦门冬 | Dwarf lilyturf | Ophiopogon japonicus |
| H0005 | Huo Xiang Ye | 藿香叶 | Patchouli | Pogostemon cablin |
Ckey description of the interaction between compound and target