Compound Description
| ID: C1179 | Common name: Betulin |
| IUPAC: (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol | CAS: CAS:473-98-3 |
| Chembl ID: CHEMBL23236 | Pubchem ID: CID:72326 |
| Formula: C30H50O2 | TCM-ID: TCMC803 |
| Smiles: OC[C@@]12CC[C@H]([C@@H]2[C@@H]2[C@](CC1)(C)[C@]1(C)CC[C@@H]3[C@]([C@H]1CC2)(C)CC[C@@H](C3(C)C)O)C(=C)C | |
| Alias:
Lup-20(29)-ene-3β,28-diol;
Lup-20(30)-ene-3β,28-diol; (3β)-Lup-20(29)-ene-3,28-diol; 3aH-Cyclopenta[a]chrysene, lup-20(29)-ene-3,28-diol deriv.; (+)-Betulin; 3,28-Dihydroxy-lupeol; 3β,28-Dihydroxylup-20(29)-ene; Betulin; Betuline; Betulinic alcohol; Betulinol; Betulol; NSC 4644; Trochol |
Structure:
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Related Targets (Total: 6)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T29MD1 | Mitogen-activated protein kinase 8 | MAPK8 |
P45983 |
A | 1 Reference(s) |
| T33OSQ | Sterol regulatory element-binding protein 1 | SREBF1 |
P36956 |
A | 2 Reference(s) |
| T37VLU | Interferon gamma | IFNG |
P01579 |
A | 1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
A | 1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
B | 1 Reference(s) |
| T20H9F | Stromelysin-1 | MMP3 |
P08254 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 32)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1225 | Huai Mi | 槐米 | NA | Sophora japonica |
| H0296 | Niu Teng | 牛藤 | twotooth achyranthes root | Achyranthes bidentata |
| H1016 | Du Zhong Tan | 杜仲炭 | Eucommia | Eucommia ulmoides |
| H1227 | Huai Zhi | 槐枝 | NA | Sophora japonica |
| H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
| H1015 | Du Zhong | 杜仲 | Eucommia | Eucommia ulmoides |
| H0507 | Song Zhi | 松脂 | Rosin | Pinus massoniana |
| H0229 | Mao Da Ding Cao | 毛大丁草 | Pilose gerbera | Gerbera piloselloides |
| H0206 | Ma Wei Song Gen | 马尾松根 | NA | Pinus massoniana |
| H0297 | Niu Xi | 牛膝 | Twotooth achyranthes | Achyranthes bidentata |
| H0207 | Ma Wei Song Shu Gen | 马尾松树根 | NA | Pinus massoniana |
| H0300 | Nv Zhen Zi | 女贞子 | Glossy privet fruit | Ligustrum lucidum |
| H1017 | Du Zhong Ye | 杜仲叶 | Eucommia leaf | Eucommia ulmoides |
| H1004 | Bai Cha | 白茶 | White tea | Camellia sinensis |
| H0855 | Chuan Bei Mu | 川贝母 | Fritillaria unibracteata | Fritillaria cirrhosa |
| H0801 | Chong Bai La | 虫白蜡 | Cera chinensis wax | Ericerus pela |
| H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |
| H0829 | Zhu Jie Xiang Fu | 竹节香附 | rhizome of radde anemone | Anemone raddeana |
| H0989 | Ding Kui Cao | 丁葵草 | Herb of twinleaf zornia | Kummerowia striata |
| H1222 | Huai Hua | 槐花 | flower bud of japanese pagodatree | Sophora japonica |
| H0361 | Ren Zi Cao | 人字草 | Herb of twinleaf zornia | Kummerowia striata |
| H1224 | Huai Jiao | 槐角 | pod of japanese pagodatree | Sophora japonica |
| H0506 | Song Xiang | 松香 | Colophony | Pinus massoniana |
| H1211 | Bai Mei | 白眉 | pilose gerbera herb | Gerbera piloselloides |
| H0060 | Jin Si Ku Lian | 金丝苦楝 | NA | Cardiospermum halicacabum |
| H0637 | Cha Ye | 茶叶 | Common tea | Camellia sinensis |
| H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
| H0318 | Pu Tao(1) | 蒲桃 | Syzygium | Syzygium jambos |
| H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
| H0020 | Ji Yan Cao | 鸡眼草 | Striate kummerowia | Kummerowia striata |
| H0762 | Yu Li Ren | 郁李仁 | NA | Prunus japonica |
| H0859 | Chuan Bei Mu Liu Jin Gao | 川贝母流浸膏 | Fritillaria unibracteata | Fritillaria cirrhosa |
Ckey description of the interaction between compound and target