Compound Description
| ID: C1249 | Common name: Codeine |
| IUPAC: (4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol | CAS: CAS:76-57-3 |
| Chembl ID: CHEMBL485 | Pubchem ID: CID:5284371 |
| Formula: C18H21NO3 | TCM-ID: TCMC929 |
| Smiles: CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(C=C4)O | |
| Alias:
Morphinan-6α-ol, 7,8-didehydro-4,5α-epoxy-3-methoxy-17-methyl-;
(5α,6α)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol; (-)-Codeine; 3-Methylmorphine; Codeine; Codicept; Coducept; Kodelak fito; Methylmorphine; Morphine 3-methyl ether; Morphine monomethyl ether; Mytussin; O3-Methylmorphine; l-Codeine |
Structure:
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Related Targets (Total: 3)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T66YJ0 | Mu-type opioid receptor | OPRM1 |
P35372 |
A | 1 Reference(s) |
| T47BNM | Solute carrier family 22 member 1 | SLC22A1 |
O15245 |
A | 1 Reference(s) |
| T76TBD | UDP-glucuronosyltransferase 2B4 | UGT2B4 |
P06133 |
A | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 5)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0248 | Mi Ying Su Ke | 蜜罂粟壳 | Opium poppy | Papaver somniferum |
| H0757 | Ying Su Ke | 罂粟壳 | Opium poppy pericarp | Papaver somniferum |
| H0756 | Ying Su | 罂粟 | Opium poppy | Papaver somniferum |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
Ckey description of the interaction between compound and target