HIT-result

Type	Detail
Target ID	T05ZBL
Protein Name	Tumor necrosis factor receptor superfamily member 1B
Uniprot ID	P20333
Protein Name Alias	Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; TNF-RII; TNFR-II; p75; p80 TNF-alpha receptor; CD antigen CD120b; Etanercept
Gene ID	7133
Gene Symbol	TNFRSF1B
Gene Alias	TNFBR; TNFR2
TTD	T53033: Research target
Pfam	PF00020
GO	0005634:nucleus 0005031:tumor necrosis factor-activated receptor activity 0008630:intrinsic apoptotic signaling pathway in response to DNA damage 2001141:regulation of RNA biosynthetic process 0019221:cytokine-mediated signaling pathway 0150077:regulation of neuroinflammatory response 0031625:ubiquitin protein ligase binding 0051044:positive regulation of membrane protein ectodomain proteolysis 0060548:negative regulation of cell death 0016020:membrane 0035579:specific granule membrane 0048714:positive regulation of oligodendrocyte differentiation 1901215:negative regulation of neuron death 0006954:inflammatory response 0002947:tumor necrosis factor receptor superfamily complex 0005576:extracellular region 0016021:integral component of membrane 0045121:membrane raft 0097191:extrinsic apoptotic signaling pathway 0150079:negative regulation of neuroinflammatory response 0003176:aortic valve development 0031643:positive regulation of myelination 0043312:neutrophil degranulation 0010614:negative regulation of cardiac muscle hypertrophy 0150098:glial cell-neuron signaling 1902339:positive regulation of apoptotic process involved in morphogenesis 0050779:RNA destabilization 0003177:pulmonary valve development 0003332:negative regulation of extracellular matrix constituent secretion 0071222:cellular response to lipopolysaccharide 0031641:regulation of myelination 0043196:varicosity 0043025:neuronal cell body 0005886:plasma membrane 0033209:tumor necrosis factor-mediated signaling pathway 0043120:tumor necrosis factor binding 0007568:aging 0002718:regulation of cytokine production involved in immune response 0042129:regulation of T cell proliferation 0002724:regulation of T cell cytokine production 0048471:perinuclear region of cytoplasm 0071363:cellular response to growth factor stimulus
PDB	3ALQ ; 1CA9
Drugbank	DB11626
KEGG	hsa:7133

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Name: Arachidonic Acid

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0195	Ma Chi Xian	马齿苋	Purslane	Portulaca oleracea
H0895	Chuan Yu Jin	川郁金	Turmeric	Curcuma longa
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0461	Shi Jun Zi Ren	使君子仁	NA	Combretum indicum
H0028	Jiang Huang	姜黄	Common turmeric	Curcuma longa
H0919	Cui Yun Cao	翠云草	Hooked spikemoss	Selaginella uncinata
H0003	Huo Ma Ren	火麻仁	Hemp fimble seed	Cannabis sativa
H0204	Ma Ren	麻仁	NA	Cannabis sativa
H0484	Shui Fei Ji	水飞蓟	St marys	Silybum marianum
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens