HIT-result

Target Description

Type	Detail
Target ID	T10RBK
Protein Name	Atrial natriuretic peptide receptor 2
Uniprot ID	P20594
Protein Name Alias	EC 4.6.1.2; Atrial natriuretic peptide receptor type B; ANP-B; ANPR-B; NPR-B; Guanylate cyclase B; GC-B
Gene ID	4882
Gene Symbol	NPR2
Gene Alias	ANPRB
TTD	T37808: Clinical Trial target
Pfam	PF01094 ; PF00211 ; PF07714
GO	0042802:identical protein binding 0017046:peptide hormone binding 0004672:protein kinase activity 0042562:hormone binding 0097011:cellular response to granulocyte macrophage colony-stimulating factor stimulus 1900194:negative regulation of oocyte maturation 0004383:guanylate cyclase activity 0022414:reproductive process 0019934:cGMP-mediated signaling 0001503:ossification 0006182:cGMP biosynthetic process 0016941:natriuretic peptide receptor activity 0001653:peptide receptor activity 0005887:integral component of plasma membrane 0060348:bone development 0005524:ATP binding 0007168:receptor guanylyl cyclase signaling pathway 0005886:plasma membrane 0051447:negative regulation of meiotic cell cycle 0010753:positive regulation of cGMP-mediated signaling 1903779:regulation of cardiac conduction 0007165:signal transduction 0005525:GTP binding 0008217:regulation of blood pressure
PDB	NA
Drugbank	DB04899 ; DB01613
KEGG	hsa:4882

Type

Detail

Target ID

T10RBK

Protein Name

Atrial natriuretic peptide receptor 2

Uniprot ID

P20594

Protein Name Alias

EC 4.6.1.2; Atrial natriuretic peptide receptor type B; ANP-B; ANPR-B; NPR-B; Guanylate cyclase B; GC-B

Gene ID

4882

Gene Symbol

NPR2

Gene Alias

ANPRB

TTD

T37808: Clinical Trial target

Pfam

PF01094 ; PF00211 ; PF07714

0042802:identical protein binding

0017046:peptide hormone binding

0004672:protein kinase activity

0042562:hormone binding

0097011:cellular response to granulocyte macrophage colony-stimulating factor stimulus

1900194:negative regulation of oocyte maturation

0004383:guanylate cyclase activity

0022414:reproductive process

0019934:cGMP-mediated signaling

0001503:ossification

0006182:cGMP biosynthetic process

0016941:natriuretic peptide receptor activity

0001653:peptide receptor activity

0005887:integral component of plasma membrane

0060348:bone development

0005524:ATP binding

0007168:receptor guanylyl cyclase signaling pathway

0005886:plasma membrane

0051447:negative regulation of meiotic cell cycle

0010753:positive regulation of cGMP-mediated signaling

1903779:regulation of cardiac conduction

0007165:signal transduction

0005525:GTP binding

0008217:regulation of blood pressure

PDB

Drugbank

DB04899 ; DB01613

KEGG

hsa:4882

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0521	Tai Pan Zu Zhi Fen	胎盘组织粉	NA	Human placenta
H0077	Jiu	酒	Ethanol	Vinum
H1102	Gu Sui Bu	骨碎补	Fortune’s drynaria rhizome	Drynaria fortunei
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0382	San Qi Hua	三七花	Sanchi	Panax notoginseng
H0236	Mao She Xiang Jin Gao	毛麝香浸膏	Abelmusk	Moschus moschiferus
H0661	Xiao Hei Dou	小黑豆	Black turtle bean	Phaseolus vulgaris
H0356	Ren Gong She Xiang	人工麝香	Abelmusk	Moschus moschiferus
H0520	Tai Pan Fen	胎盘粉	Fetus powder	Human placenta
H0381	San Qi Gao Fen	三七膏粉	Sanchi	Panax notoginseng
H0380	San Qi Gan Jin Gao	三七干浸膏	Sanchi	Panax notoginseng
H0385	San Qi Ye Jing	三七叶茎	Sanchi	Panax notoginseng
H0384	San Qi Ye	三七叶	Folium panax notoginseng	Panax notoginseng
H0383	San Qi Jing Ye	三七茎叶	Sanchi	Panax notoginseng
H0437	She Xiang	麝香	Abelmusk	Moschus moschiferus
H0235	Mao She Xiang	毛麝香	Abelmusk	Moschus moschiferus
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 17)