HIT-result

Target Description

Type	Detail
Target ID	T11AJ4
Protein Name	WW domain-containing oxidoreductase
Uniprot ID	Q9NZC7
Protein Name Alias	EC 1.1.1.-; Fragile site FRA16D oxidoreductase; Short chain dehydrogenase/reductase family 41C member 1
Gene ID	51741
Gene Symbol	WWOX
Gene Alias	FOR; SDR41C1; WOX1
TTD	NA
Pfam	PF00397 ; PF00106
GO	0042802:identical protein binding 0005634:nucleus 0005829:cytosol 0003713:transcription coactivator activity 0090575:RNA polymerase II transcription regulator complex 0071560:cellular response to transforming growth factor beta stimulus 0072332:intrinsic apoptotic signaling pathway by p53 class mediator 0019899:enzyme binding 0016055:Wnt signaling pathway 0048705:skeletal system morphogenesis 0030178:negative regulation of Wnt signaling pathway 0097191:extrinsic apoptotic signaling pathway 0001649:osteoblast differentiation 0005794:Golgi apparatus 0000122:negative regulation of transcription by RNA polymerase II 0005739:mitochondrion 0005737:cytoplasm 2001241:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 0005654:nucleoplasm 0016491:oxidoreductase activity 2001238:positive regulation of extrinsic apoptotic signaling pathway 0045944:positive regulation of transcription by RNA polymerase II
PDB	1WMV
Drugbank	NA
KEGG	hsa:51741

Type

Detail

Target ID

T11AJ4

Protein Name

WW domain-containing oxidoreductase

Uniprot ID

Q9NZC7

Protein Name Alias

EC 1.1.1.-; Fragile site FRA16D oxidoreductase; Short chain dehydrogenase/reductase family 41C member 1

Gene ID

51741

Gene Symbol

WWOX

Gene Alias

FOR; SDR41C1; WOX1

TTD

Pfam

PF00397 ; PF00106

0042802:identical protein binding

0005634:nucleus

0005829:cytosol

0003713:transcription coactivator activity

0090575:RNA polymerase II transcription regulator complex

0071560:cellular response to transforming growth factor beta stimulus

0072332:intrinsic apoptotic signaling pathway by p53 class mediator

0019899:enzyme binding

0016055:Wnt signaling pathway

0048705:skeletal system morphogenesis

0030178:negative regulation of Wnt signaling pathway

0097191:extrinsic apoptotic signaling pathway

0001649:osteoblast differentiation

0005794:Golgi apparatus

0000122:negative regulation of transcription by RNA polymerase II

0005739:mitochondrion

0005737:cytoplasm

2001241:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

0005654:nucleoplasm

0016491:oxidoreductase activity

2001238:positive regulation of extrinsic apoptotic signaling pathway

0045944:positive regulation of transcription by RNA polymerase II

PDB

1WMV

Drugbank

KEGG

hsa:51741

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0521	Tai Pan Zu Zhi Fen	胎盘组织粉	NA	Human placenta
H0437	She Xiang	麝香	Abelmusk	Moschus moschiferus
H0235	Mao She Xiang	毛麝香	Abelmusk	Moschus moschiferus
H0661	Xiao Hei Dou	小黑豆	Black turtle bean	Phaseolus vulgaris
H0356	Ren Gong She Xiang	人工麝香	Abelmusk	Moschus moschiferus
H0380	San Qi Gan Jin Gao	三七干浸膏	Sanchi	Panax notoginseng
H0382	San Qi Hua	三七花	Sanchi	Panax notoginseng
H0381	San Qi Gao Fen	三七膏粉	Sanchi	Panax notoginseng
H0383	San Qi Jing Ye	三七茎叶	Sanchi	Panax notoginseng
H0236	Mao She Xiang Jin Gao	毛麝香浸膏	Abelmusk	Moschus moschiferus
H1102	Gu Sui Bu	骨碎补	Fortune’s drynaria rhizome	Drynaria fortunei
H0077	Jiu	酒	Ethanol	Vinum
H0384	San Qi Ye	三七叶	Folium panax notoginseng	Panax notoginseng
H0520	Tai Pan Fen	胎盘粉	Fetus powder	Human placenta
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0385	San Qi Ye Jing	三七叶茎	Sanchi	Panax notoginseng
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 17)