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Target Description
Type
Detail
Target ID
T23WX7
Protein Name
Nuclear receptor coactivator 1
Uniprot ID
Q15788
Protein Name Alias
NCoA-1; EC 2.3.1.48; Class E basic helix-loop-helix protein 74; bHLHe74; Protein Hin-2; RIP160; Renal carcinoma antigen NY-REN-52; Steroid receptor coactivator 1; SRC-1
Gene ID
8648
Gene Symbol
NCOA1
Gene Alias
BHLHE74; SRC1
TTD
NA
Pfam
PF00010
;
PF08832
;
PF08815
;
PF00989
;
PF07469
GO
0005634:nucleus
0060713:labyrinthine layer morphogenesis
0007595:lactation
0002155:regulation of thyroid hormone mediated signaling pathway
0005829:cytosol
0033142:progesterone receptor binding
0046983:protein dimerization activity
0017162:aryl hydrocarbon receptor binding
0060179:male mating behavior
0030374:nuclear receptor coactivator activity
0016922:nuclear receptor binding
0032991:protein-containing complex
0019216:regulation of lipid metabolic process
0005654:nucleoplasm
0032526:response to retinoic acid
0019899:enzyme binding
0032870:cellular response to hormone stimulus
0045893:positive regulation of transcription, DNA-templated
0045944:positive regulation of transcription by RNA polymerase II
0044849:estrous cycle
0003682:chromatin binding
0043967:histone H4 acetylation
0021854:hypothalamus development
0045666:positive regulation of neuron differentiation
0044877:protein-containing complex binding
0030522:intracellular receptor signaling pathway
0046965:retinoid X receptor binding
0000435:positive regulation of transcription from RNA polymerase II promoter by galactose
0021766:hippocampus development
0032570:response to progesterone
0008584:male gonad development
0000977:RNA polymerase II transcription regulatory region sequence-specific DNA binding
0003713:transcription coactivator activity
0043065:positive regulation of apoptotic process
2001038:regulation of cellular response to drug
0021549:cerebellum development
0015721:bile acid and bile salt transport
0005886:plasma membrane
0047485:protein N-terminus binding
0045925:positive regulation of female receptivity
1904017:cellular response to Thyroglobulin triiodothyronine
0035257:nuclear hormone receptor binding
0043005:neuron projection
0032355:response to estradiol
0030331:estrogen receptor binding
0021987:cerebral cortex development
0000785:chromatin
0004402:histone acetyltransferase activity
PDB
1KV6
;
1K74
;
5Q0T
;
6A5X
;
5Q11
;
6SSQ
;
3BEJ
;
5AVL
;
5E7V
;
3OMQ
;
5DV8
;
4JYG
;
5Q0W
;
5Q1H
;
3OOF
;
1XVP
;
6P9F
;
3BQD
;
5Q0P
;
4MG6
;
2P54
;
4HEE
;
6A60
;
5NWM
;
4Y29
;
3UU7
;
5MWP
;
5Q0V
;
5Q18
;
5GTO
;
4DM6
;
5Q0U
;
6A5Z
;
1RDT
;
4MGC
;
4G1Z
;
3OLL
;
3OMP
;
7BQ0
;
5GTP
;
3FUR
;
3FEI
;
5OWD
;
7BQ1
;
6IJR
;
3IPU
;
3UUA
;
7BPZ
;
3G8I
;
5DVC
;
3OKH
;
5DWL
;
5Q1G
;
3HC5
;
3RVF
;
6HTY
;
3FXV
;
3OOK
;
1X78
;
3QT0
;
5Q19
;
6T2M
;
4MGB
;
4F9M
;
5JMM
;
5DV6
;
3DCT
;
4TUZ
;
2PRG
;
5DSH
;
6NX1
;
5Y44
;
1U3S
;
5AVI
;
3DCU
;
6A5Y
;
1U3R
;
6BNS
;
7BPY
;
5L7G
;
4MGA
;
6W9I
;
5NMA
;
3LMP
;
1XIU
;
5Q1B
;
4DQM
;
7BQ4
;
5OW9
;
2C52
;
5Q15
;
5Q0R
;
5X0R
;
1FM9
;
5Q12
;
3T03
;
4G20
;
3P89
;
4DM8
;
5Q1A
;
6ILQ
;
5Q0K
;
4JYH
;
5Q13
;
3G9E
;
2HBH
;
5GTN
;
5L7E
;
5X8U
;
2HFP
;
5OW7
;
7BQ3
;
4TV1
;
3RUT
;
6L96
;
3OLF
;
3S9S
;
5X8W
;
3ET3
;
5MX7
;
2NV7
;
3OKI
;
5YCN
;
6W9H
;
6GG8
;
2GTK
;
5Q1I
;
1YYE
;
5HJS
;
5NMB
;
1ZAF
;
6FO8
;
3RUU
;
1TFC
;
1X7B
;
5Q1D
;
4FGY
;
4MG7
;
1K4W
;
4DK8
;
3GYT
;
3IPQ
;
6IJS
;
1NQ7
;
3CTB
;
5NKY
;
5Q14
;
4G21
;
6ITM
;
5JI0
;
1PZL
;
3HVL
;
6FO7
;
4RUP
;
5YP6
;
3OMM
;
4DK7
;
6ICJ
;
5Q0N
;
4G1D
;
3KMR
;
3ET1
;
3IPS
;
5A86
;
6FO9
;
2HCD
;
4J5X
;
2FVJ
;
5DV3
;
1YY4
;
5Q0M
;
5Q0J
;
5MWY
;
6JNR
;
6JQ7
;
1X76
;
4MG5
;
6A5W
;
2NPA
;
1N4H
;
1P8D
;
1K7L
;
4MG9
;
5Q0Y
;
6TFI
;
3H0A
;
3OLS
;
5Q1C
;
4RUJ
;
6KTN
;
1XV9
;
7BQ2
;
6FOB
;
5Q0S
;
5L7H
;
5Q16
;
1X7J
;
5Q0Q
;
6GEV
;
3DR1
;
3OMO
;
6U25
;
6XP9
;
5Q1F
;
4G2H
;
5Q0X
;
4UDB
;
1NRL
;
4JYI
;
4G1Y
;
4MG8
;
5AZT
;
3GYU
;
3CWD
;
5YCP
;
3P88
;
3V9Y
;
3FEJ
;
5Q1E
;
6KTM
;
3HC6
;
5Q10
;
5Q0O
;
3VN2
;
6E3G
;
2A3I
;
3OMK
;
5Q0L
;
1FM6
;
7JYM
;
5Q0Z
;
6FOD
;
3UUD
;
4MGD
;
4UDA
;
2HC4
Drugbank
DB04652
;
DB06832
;
DB06908
;
DB08915
;
DB01645
;
DB07724
;
DB08220
;
DB07150
;
DB08231
;
DB08742
;
DB07198
;
DB06927
;
DB07009
;
DB06875
;
DB07236
;
DB07080
;
DB07215
;
DB07230
;
DB07530
;
DB07557
;
DB07119
KEGG
hsa:8648
Related Compounds (Total: 2)
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C0112
Name: Gossypol
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C0415
Name: Stanolone
Related Herbs (Total: 3)
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Herb id
Chinese Pin Yin
Chinese Character
English Name
Latin Name
H0847
Zi He Che
紫河车
Human placenta
Homo sapiens
H0253
Mian Hua Gen
棉花根
Levant cotton root
Gossypium herbaceum
H0360
Ren Zhong Bai
人中白
Human urine sediment
Homo sapiens