ID: C0112 | Common name: Gossypol |
IUPAC: 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde | CAS: CAS:303-45-7 |
Chembl ID: CHEMBL51483 | Pubchem ID: CID:3503 |
Formula: C30H30O8 | TCM-ID: TCMC1287 |
Smiles: CC1=CC2=C(C(=C(C(=C2C(C)C)O)O)C=O)C(=C1C3=C(C4=C(C=C3C)C(=C(C(=C4C=O)O)O)C(C)C)O)O | |
Alias:
[2,2'-Binaphthalene]-8,8'-dicarboxaldehyde, 1,1',6,6',7,7'-hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-;
1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)[2,2'-binaphthalene]-8,8'-dicarboxaldehyde; (±)-Gossypol; 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-diisopropyl-2,2'-binaphthyl-8,8'-dialdehyde; 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-diisopropyl[2,2'-binaphthalene]-8,8'-dicarboxaldehyde; 1,1',6,6',7,7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-2,2'-binaphthalene-8,8'-dicarboxaldehyde; 1,6,7,1',6',7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2']binaphthalenyl-8,8'-dicarboxaldehyde; 2,2'-Bis[1,6,7-trihydroxy-3-methyl-5-isopropyl-8-aldehydonaphthyl]; 2,2'-Bis[8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthyl]; BL 193; Gossypol; NSC 56817; NSC 624336; No Fertil; Pogosin; Tash 1 |
Structure:
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Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
---|---|---|---|---|---|
T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
A | 6 Reference(s) |
T23WX7 | Nuclear receptor coactivator 1 | NCOA1 |
Q15788 |
A | 1 Reference(s) |
T08KTR | Nuclear receptor coactivator 3 | NCOA3 |
Q9Y6Q9 |
A | 2 Reference(s) |
T74I49 | Bcl-2-like protein 1 | BCL2L1 |
Q07817 |
A | 6 Reference(s) |
T39M81 | DNA-(apurinic or apyrimidinic site) endonuclease | APEX1 |
P27695 |
A | 1 Reference(s) |
T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
A | 1 Reference(s) |
T55Z0P | L-lactate dehydrogenase A chain | LDHA |
P00338 |
A | 2 Reference(s) |
T77DWZ | PCNA-associated factor | PCLAF |
Q15004 |
A | 1 Reference(s) |
T40DIM | Corticosteroid 11-beta-dehydrogenase isozyme 1 | HSD11B1 |
P28845 |
A | 1 Reference(s) |
T38T1U | Caspase-8 | CASP8 |
Q14790 |
B | 1 Reference(s) |
T85U8U | Caspase-3 | CASP3 |
P42574 |
B | 1 Reference(s) |
T54CIF | Interleukin-8 | CXCL8 |
P10145 |
B | 1 Reference(s) |
T23P74 | Caspase-9 | CASP9 |
P55211 |
B | 1 Reference(s) |
T76B0A | Gap junction alpha-1 protein | GJA1 |
P17302 |
B | 1 Reference(s) |
T14JSX | Plasminogen | PLG |
P00747 |
B | 1 Reference(s) |
T13YN2 | Bcl-2-like protein 1 | Bcl2l1 |
Q64373 |
B | 1 Reference(s) |
Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
---|---|---|---|---|
H0253 | Mian Hua Gen | 棉花根 | Levant cotton root | Gossypium herbaceum |