Target Description

Type Detail
Target ID T29C64
Protein Name Calcitonin gene-related peptide 1
Uniprot ID P06881
; P01258
Protein Name Alias NA
Gene ID 796
Gene Symbol CALCA
Gene Alias CALC1
TTD T93509: Clinical Trial target
Pfam PF00214
GO
0001878:response to yeast

0042802:identical protein binding

0005634:nucleus

0007568:aging

0097647:amylin receptor signaling pathway

0050829:defense response to Gram-negative bacterium

0007218:neuropeptide signaling pathway

0045776:negative regulation of blood pressure

0001944:vasculature development

0007631:feeding behavior

0032730:positive regulation of interleukin-1 alpha production

0031716:calcitonin receptor binding

1990090:cellular response to nerve growth factor stimulus

0001976:nervous system process involved in regulation of systemic arterial blood pressure

0007204:positive regulation of cytosolic calcium ion concentration

0043542:endothelial cell migration

0001935:endothelial cell proliferation

0032147:activation of protein kinase activity

0030279:negative regulation of ossification

0045892:negative regulation of transcription, DNA-templated

1990408:calcitonin gene-related peptide receptor signaling pathway

0051480:regulation of cytosolic calcium ion concentration

0007189:adenylate cyclase-activating G protein-coupled receptor signaling pathway

0019732:antifungal humoral response

0031623:receptor internalization

0005615:extracellular space

0042311:vasodilation

0045671:negative regulation of osteoclast differentiation

0044877:protein-containing complex binding

0045986:negative regulation of smooth muscle contraction

0010523:negative regulation of calcium ion transport into cytosol

0002862:negative regulation of inflammatory response to antigenic stimulus

0071356:cellular response to tumor necrosis factor

0002031:G protein-coupled receptor internalization

0005179:hormone activity

0009408:response to heat

0043195:terminal bouton

0007190:activation of adenylate cyclase activity

0001984:artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure

0002548:monocyte chemotaxis

0008016:regulation of heart contraction

0007267:cell-cell signaling

1990000:amyloid fibril formation

0048265:response to pain

0045651:positive regulation of macrophage differentiation

0006954:inflammatory response

0051482:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway

0032757:positive regulation of interleukin-8 production

0006468:protein phosphorylation

0005576:extracellular region

0005102:signaling receptor binding

0007159:leukocyte cell-cell adhesion

0005737:cytoplasm

0050830:defense response to Gram-positive bacterium

0007186:G protein-coupled receptor signaling pathway

0007566:embryo implantation

0061844:antimicrobial humoral immune response mediated by antimicrobial peptide

0043025:neuronal cell body

0008217:regulation of blood pressure

0050965:detection of temperature stimulus involved in sensory perception of pain

0019731:antibacterial humoral response

0045779:negative regulation of bone resorption

0045087:innate immune response

PDB 2JXZ ; 1LS7 ; 6E3Y
Drugbank DB12228 ; DB14042 ; DB14040 ; DB14041 ; DB04869
KEGG hsa:796

Related Compounds  (Total: 6)

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C0376
Name: Rutaecarpine
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C0581
Name: Piperidine
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C0848
Name: Acetaminophen
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C0926
Name: Rutaecarpine
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C1196
Name: Bradykinin


Related Herbs  (Total: 18)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1228 Huang Bai黄柏 Amur corktreePhellodendron amurense
H0123 La Jiao Liu Jin Gao辣椒流浸膏 Bush redpepperCapsicum frutescens
H0704 Yan Guan Huang Bai盐关黄柏 Amur cork treePhellodendron amurense
H1230 Huang Bai Fen黄柏粉 Amur corktreePhellodendron amurense
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0227 Mang Guo Ye芒果叶 Mango leafMangifera indica
H0616 Wu Zhu Yu吴茱萸 Medicinal evodiaEvodia rutaecarpa
H0295 Bi Ba荜茇 Long pepperPiper longum
H0121 La Jiao Jin Chu Ye辣椒浸出液 Bush redpepperCapsicum frutescens
H0122 La Jiao Jin Gao辣椒浸膏 Bush redpepperCapsicum frutescens
H0242 Bei Sha Shen Liu Jin Gao北沙参流浸膏 Glehnia littoralisGlehnia littoralis
H0119 La Jiao辣椒 Bush redpepperCapsicum frutescens
H0239 Bei Sha Shen北沙参 Coastal glehniaGlehnia littoralis
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H1115 Guan Huang Bai关黄柏 Amur cork treePhellodendron amurense
H0854 Zi Wei Gen Pi紫葳根皮 NACampsis grandiflora
H0458 Shi Hu石斛 DendrobiumHerba dendrobii
H1231 Huang Bai Tan黄柏炭 Amur corktreePhellodendron amurense