Target Description

Type Detail
Target ID T29PSX
Protein Name Receptor of activated protein C kinase 1
Uniprot ID P63244
Protein Name Alias Cell proliferation-inducing gene 21 protein;  Guanine nucleotide-binding protein subunit beta-2-like 1;  Guanine nucleotide-binding protein subunit beta-like protein 12.3;  Human lung cancer oncogene 7 protein;  HLC-7;  Receptor for activated C kinase;  Small ribosomal subunit protein RACK1
Gene ID 10399
Gene Symbol RACK1
Gene Alias GNB2L1
TTD T93712: Research target
Pfam PF00400
GO
0030332:cyclin binding

0070062:extracellular exosome

0015935:small ribosomal subunit

0007369:gastrulation

0050765:negative regulation of phagocytosis

0051898:negative regulation of protein kinase B signaling

0042998:positive regulation of Golgi to plasma membrane protein transport

0048511:rhythmic process

0010629:negative regulation of gene expression

2000543:positive regulation of gastrulation

0019903:protein phosphatase binding

0030425:dendrite

0030496:midbody

0051434:BH3 domain binding

0043025:neuronal cell body

0043022:ribosome binding

2001244:positive regulation of intrinsic apoptotic signaling pathway

2000304:positive regulation of ceramide biosynthetic process

0043547:positive regulation of GTPase activity

0005102:signaling receptor binding

0045879:negative regulation of smoothened signaling pathway

0001934:positive regulation of protein phosphorylation

0005080:protein kinase C binding

1903208:negative regulation of hydrogen peroxide-induced neuron death

0005829:cytosol

1990630:IRE1-RACK1-PP2A complex

0032436:positive regulation of proteasomal ubiquitin-dependent protein catabolic process

0043065:positive regulation of apoptotic process

0030308:negative regulation of cell growth

2000114:regulation of establishment of cell polarity

0071333:cellular response to glucose stimulus

0051901:positive regulation of mitochondrial depolarization

0042169:SH2 domain binding

0005737:cytoplasm

0033137:negative regulation of peptidyl-serine phosphorylation

0005654:nucleoplasm

0043204:perikaryon

0008200:ion channel inhibitor activity

0019899:enzyme binding

0030292:protein tyrosine kinase inhibitor activity

0032880:regulation of protein localization

0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process

1900102:negative regulation of endoplasmic reticulum unfolded protein response

0048471:perinuclear region of cytoplasm

0072344:rescue of stalled ribosome

0051726:regulation of cell cycle

0003723:RNA binding

0007049:cell cycle

0030335:positive regulation of cell migration

0005739:mitochondrion

0030971:receptor tyrosine kinase binding

0042803:protein homodimerization activity

0005634:nucleus

0031334:positive regulation of protein-containing complex assembly

0008656:cysteine-type endopeptidase activator activity involved in apoptotic process

0071363:cellular response to growth factor stimulus

0060090:molecular adaptor activity

0032091:negative regulation of protein binding

0045296:cadherin binding

0017148:negative regulation of translation

0051343:positive regulation of cyclic-nucleotide phosphodiesterase activity

0051302:regulation of cell division

0016567:protein ubiquitination

0001891:phagocytic cup

0035591:signaling adaptor activity

0010803:regulation of tumor necrosis factor-mediated signaling pathway

0016032:viral process

0030178:negative regulation of Wnt signaling pathway

PDB 4V6X ; 5AJ0 ; 5LKS ; 6ZN5 ; 6ZVH ; 5VYC ; 6ZM7 ; 6Y0G ; 6ZXH ; 6ZMI ; 6EK0 ; 6ZMW ; 7K5I ; 5FLX ; 6G5I ; 6Y2L ; 6FEC ; 6OLG ; 6ZOJ ; 7A09 ; 6OLF ; 6ZXD ; 4UG0 ; 6ZON ; 6OLE ; 6OLI ; 6Z6M ; 6IP5 ; 6QZP ; 6ZP4 ; 5OA3 ; 6OM7 ; 6ZMO ; 6YBS ; 6ZMT ; 6Z6L ; 6XA1 ; 6G5H ; 6IP8 ; 6Y57 ; 5A2Q ; 6OM0 ; 6G53 ; 5T2C ; 6Z6N ; 6ZLW ; 6ZME ; 6G51 ; 6ZXG ; 6IP6 ; 6ZXE ; 6G18 ; 6ZXF ; 6OLZ ; 6ZVJ ; 6ZOL ; 4AOW
Drugbank DB09130
KEGG hsa:10399

Related Compounds  (Total: 2)

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C0055
Name: Estradiol
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C0901
Name: Androstenedione


Related Herbs  (Total: 19)

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H0521 Tai Pan Zu Zhi Fen胎盘组织粉 NAHuman placenta
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