Home
Search
Target-mining
My-Target curation
Browse
Help
Target Description
Type
Detail
Target ID
T36TO2
Protein Name
Endoglin
Uniprot ID
P17813
Protein Name Alias
CD antigen CD105
Gene ID
2022
Gene Symbol
ENG
Gene Alias
END
TTD
T22350: Clinical Trial target
Pfam
PF00100
GO
0022617:extracellular matrix disassembly
0030509:BMP signaling pathway
0055009:atrial cardiac muscle tissue morphogenesis
0010862:positive regulation of pathway-restricted SMAD protein phosphorylation
0070278:extracellular matrix constituent secretion
0007179:transforming growth factor beta receptor signaling pathway
0042127:regulation of cell population proliferation
0051001:negative regulation of nitric-oxide synthase activity
0004888:transmembrane signaling receptor activity
0022009:central nervous system vasculogenesis
0003148:outflow tract septum morphogenesis
0001837:epithelial to mesenchymal transition
0060348:bone development
0016021:integral component of membrane
0010629:negative regulation of gene expression
0045766:positive regulation of angiogenesis
0050431:transforming growth factor beta binding
0060394:negative regulation of pathway-restricted SMAD protein phosphorylation
0045944:positive regulation of transcription by RNA polymerase II
0042802:identical protein binding
0043235:receptor complex
0030513:positive regulation of BMP signaling pathway
0005534:galactose binding
0051897:positive regulation of protein kinase B signaling
0005615:extracellular space
1905222:atrioventricular canal morphogenesis
1905007:positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
0001934:positive regulation of protein phosphorylation
0060326:cell chemotaxis
0005114:type II transforming growth factor beta receptor binding
0035912:dorsal aorta morphogenesis
1905065:positive regulation of vascular associated smooth muscle cell differentiation
0042060:wound healing
0007155:cell adhesion
0042325:regulation of phosphorylation
0005024:transforming growth factor beta-activated receptor activity
0006355:regulation of transcription, DNA-templated
0030336:negative regulation of cell migration
0034713:type I transforming growth factor beta receptor binding
0003084:positive regulation of systemic arterial blood pressure
0001666:response to hypoxia
0048745:smooth muscle tissue development
0001937:negative regulation of endothelial cell proliferation
0048844:artery morphogenesis
0003198:epithelial to mesenchymal transition involved in endocardial cushion formation
0031953:negative regulation of protein autophosphorylation
0072563:endothelial microparticle
0042493:response to drug
0031960:response to corticosteroid
0030512:negative regulation of transforming growth factor beta receptor signaling pathway
0009986:cell surface
0000122:negative regulation of transcription by RNA polymerase II
0042803:protein homodimerization activity
0003222:ventricular trabecula myocardium morphogenesis
0005539:glycosaminoglycan binding
0016477:cell migration
0070483:detection of hypoxia
0048870:cell motility
0005925:focal adhesion
0015026:coreceptor activity
0071260:cellular response to mechanical stimulus
0001947:heart looping
0003203:endocardial cushion morphogenesis
0017015:regulation of transforming growth factor beta receptor signaling pathway
0003208:cardiac ventricle morphogenesis
0097084:vascular associated smooth muscle cell development
0005886:plasma membrane
0001570:vasculogenesis
0048845:venous blood vessel morphogenesis
0048185:activin binding
0030155:regulation of cell adhesion
0001569:branching involved in blood vessel morphogenesis
0032967:positive regulation of collagen biosynthetic process
0016604:nuclear body
0003273:cell migration involved in endocardial cushion formation
0001525:angiogenesis
0003209:cardiac atrium morphogenesis
0009897:external side of plasma membrane
PDB
5HZV
;
5HZW
;
5I04
Drugbank
DB06322
KEGG
hsa:2022
Related Compounds (Total: 2)
download
Go to browser
C0365
Name: Retinal
Go to browser
C0987
Name: Atorvastatin
Related Herbs (Total: 5)
download
Herb id
Chinese Pin Yin
Chinese Character
English Name
Latin Name
H0358
Ren Shen Ye
人参叶
Ginseng leaf
Panax ginseng
H0847
Zi He Che
紫河车
Human placenta
Homo sapiens
H0416
Shan Shen
山参
NA
Panax ginseng
H0357
Ren Shen
人参
Ginseng
Panax ginseng
H0360
Ren Zhong Bai
人中白
Human urine sediment
Homo sapiens