Target Description

Type Detail
Target ID T43HES
Protein Name Paired box protein Pax-2
Uniprot ID Q02962
Protein Name Alias NA
Gene ID 5076
Gene Symbol PAX2
Gene Alias NA
Pfam PF12403 ; PF00292
0008134:transcription factor binding

0090190:positive regulation of branching involved in ureteric bud morphogenesis

0005815:microtubule organizing center

0001658:branching involved in ureteric bud morphogenesis

0048856:anatomical structure development

0000987:cis-regulatory region sequence-specific DNA binding

0001655:urogenital system development

0001843:neural tube closure

0035566:regulation of metanephros size

0021650:vestibulocochlear nerve formation

0072307:regulation of metanephric nephron tubule epithelial cell differentiation

0021633:optic nerve structural organization

0021631:optic nerve morphogenesis

0072162:metanephric mesenchymal cell differentiation

0072108:positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

0048793:pronephros development

0072189:ureter development

0003406:retinal pigment epithelium development

0007501:mesodermal cell fate specification

0021554:optic nerve development

0072593:reactive oxygen species metabolic process

0071333:cellular response to glucose stimulus

1900212:negative regulation of mesenchymal cell apoptotic process involved in metanephros development

0045944:positive regulation of transcription by RNA polymerase II

0043066:negative regulation of apoptotic process

0003677:DNA binding

0072205:metanephric collecting duct development

0072207:metanephric epithelium development

0072221:metanephric distal convoluted tubule development

0072179:nephric duct formation

0003337:mesenchymal to epithelial transition involved in metanephros morphogenesis

0031667:response to nutrient levels

0048854:brain morphogenesis

1900218:negative regulation of apoptotic process involved in metanephric nephron tubule development

0039003:pronephric field specification

0071300:cellular response to retinoic acid

0003700:DNA-binding transcription factor activity

0060231:mesenchymal to epithelial transition

0032993:protein-DNA complex

0048863:stem cell differentiation

0090102:cochlea development




0042472:inner ear morphogenesis

0007601:visual perception

0010001:glial cell differentiation

0002072:optic cup morphogenesis involved in camera-type eye development

0050679:positive regulation of epithelial cell proliferation


2000594:positive regulation of metanephric DCT cell differentiation

0045893:positive regulation of transcription, DNA-templated

0061360:optic chiasma development

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

1990837:sequence-specific double-stranded DNA binding

0072300:positive regulation of metanephric glomerulus development

0043069:negative regulation of programmed cell death

1900215:negative regulation of apoptotic process involved in metanephric collecting duct development

0072305:negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis

2000378:negative regulation of reactive oxygen species metabolic process

0070301:cellular response to hydrogen peroxide

0035799:ureter maturation

0071364:cellular response to epidermal growth factor stimulus

0034451:centriolar satellite

0043010:camera-type eye development

0045892:negative regulation of transcription, DNA-templated

0072289:metanephric nephron tubule formation


0000976:transcription regulatory region sequence-specific DNA binding

0001823:mesonephros development

0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

2000597:positive regulation of optic nerve formation

0043491:protein kinase B signaling

0032991:protein-containing complex

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0090103:cochlea morphogenesis

0006357:regulation of transcription by RNA polymerase II


0072075:metanephric mesenchyme development

0001709:cell fate determination

Drugbank NA
KEGG hsa:5076

Related Compounds  (Total: 1)

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Name: Matrine

Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0111 Ku Shen苦参 Lightyellow sophoraSophora flavescens
H0405 Shan Dou Gen山豆根 Tonkin sophora rootSophora subprostrata