HIT-result

Type	Detail
Target ID	T47F9W
Protein Name	Galectin-3
Uniprot ID	P17931
Protein Name Alias	Gal-3; 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen
Gene ID	3958
Gene Symbol	LGALS3
Gene Alias	MAC2
TTD	T72038: Clinical Trial target
Pfam	PF00337
GO	0042056:chemoattractant activity 0070062:extracellular exosome 0002548:monocyte chemotaxis 0030246:carbohydrate binding 0005615:extracellular space 0030667:secretory granule membrane 0019903:protein phosphatase binding 0004864:protein phosphatase inhibitor activity 0016020:membrane 0101003:ficolin-1-rich granule membrane 0005743:mitochondrial inner membrane 0009986:cell surface 0006397:mRNA processing 0045637:regulation of myeloid cell differentiation 0048246:macrophage chemotaxis 0043236:laminin binding 0050860:negative regulation of T cell receptor signaling pathway 0005576:extracellular region 1903614:negative regulation of protein tyrosine phosphatase activity 0062023:collagen-containing extracellular matrix 2001237:negative regulation of extrinsic apoptotic signaling pathway 0031640:killing of cells of other organism 0005886:plasma membrane 0061844:antimicrobial humoral immune response mediated by antimicrobial peptide 0045087:innate immune response 0030855:epithelial cell differentiation 0050918:positive chemotaxis 0005737:cytoplasm 0044216:other organism cell 0071677:positive regulation of mononuclear cell migration 0070232:regulation of T cell apoptotic process 0003723:RNA binding 0048245:eosinophil chemotaxis 0043312:neutrophil degranulation 2000521:negative regulation of immunological synapse formation 1902041:regulation of extrinsic apoptotic signaling pathway via death domain receptors 0005634:nucleus 0031334:positive regulation of protein-containing complex assembly 0042129:regulation of T cell proliferation 0045806:negative regulation of endocytosis 1903078:positive regulation of protein localization to plasma membrane 2001189:negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 0008380:RNA splicing 0019863:IgE binding 0090280:positive regulation of calcium ion import 0001772:immunological synapse 0030593:neutrophil chemotaxis 0071674:mononuclear cell migration 0070492:oligosaccharide binding 0005681:spliceosomal complex
PDB	3AYE ; 6RHM ; 4XBN ; 6I77 ; 1A3K ; 6QLP ; 5H9P ; 6EOL ; 4R9C ; 6QLO ; 4JCK ; 5EXO ; 6QLR ; 6EOG ; 6KXA ; 5NFC ; 6I76 ; 5ODY ; 6G0V ; 5E8A ; 5IUQ ; 5NF9 ; 6QLQ ; 6I74 ; 4LBO ; 5E88 ; 6FOF ; 3AYC ; 4RL7 ; 5NFB ; 6QGE ; 6QLU ; 2NMO ; 2NMN ; 3ZSJ ; 5H9R ; 6Y4C ; 6RZK ; 6F2Q ; 3ZSM ; 4R9B ; 4R9A ; 4LBJ ; 6Q17 ; 1KJR ; 3T1L ; 2NN8 ; 6RZJ ; 6QLT ; 4LBL ; 6RZM ; 1KJL ; 6TF6 ; 6TF7 ; 6Y78 ; 4BLJ ; 5NFA ; 6I75 ; 6RHL ; 6RZG ; 6RZL ; 3ZSL ; 6F6Y ; 5OAX ; 3ZSK ; 6QLS ; 3T1M ; 4BLI ; 4BM8 ; 6EYM ; 6B8K ; 5E89 ; 3AYA ; 4LBN ; 2XG3 ; 4R9D ; 6EXY ; 6QLN ; 4LBM ; 6QGF ; 6FK2 ; 6H64 ; 6I78 ; 6RZF ; 6KXB ; 4JC1 ; 5NF7 ; 6Q0Q ; 4LBK ; 6RZH ; 6RZI ; 3AYD
Drugbank	DB01827 ; DB04465
KEGG	hsa:3958

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Name: Morin

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Name: Cynaropicrin

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Name: Morin

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Name: Atorvastatin

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Name: pectin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0274	Mu Xiang	木香	Common aucklandia	Saussurea lappa
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba