Target Description

Type Detail
Target ID T47WWK
Protein Name C-C chemokine receptor type 1
Uniprot ID P32246
Protein Name Alias C-C CKR-1;  CC-CKR-1;  CCR-1;  CCR1;  HM145;  LD78 receptor;  Macrophage inflammatory protein 1-alpha receptor;  MIP-1alpha-R;  RANTES-R;  CD antigen CD191
Gene ID 1230
Gene Symbol CCR1
Gene Alias CMKBR1;  CMKR1;  SCYAR1
TTD T16016: Clinical Trial target
Pfam PF00001
GO
0006887:exocytosis

0070098:chemokine-mediated signaling pathway

0010629:negative regulation of gene expression

0007187:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

0007204:positive regulation of cytosolic calcium ion concentration

0035717:chemokine (C-C motif) ligand 7 binding

0090026:positive regulation of monocyte chemotaxis

0007186:G protein-coupled receptor signaling pathway

0071791:chemokine (C-C motif) ligand 5 binding

0060326:cell chemotaxis

0051928:positive regulation of calcium ion transport

0009611:response to wounding

0016493:C-C chemokine receptor activity

0009897:external side of plasma membrane

0006816:calcium ion transport

0002407:dendritic cell chemotaxis

0007166:cell surface receptor signaling pathway

0007267:cell-cell signaling

0005886:plasma membrane

0005737:cytoplasm

0045672:positive regulation of osteoclast differentiation

0005887:integral component of plasma membrane

0030335:positive regulation of cell migration

0006955:immune response

0019221:cytokine-mediated signaling pathway

0006874:cellular calcium ion homeostasis

0004435:phosphatidylinositol phospholipase C activity

0030502:negative regulation of bone mineralization

0006935:chemotaxis

0070374:positive regulation of ERK1 and ERK2 cascade

0006954:inflammatory response

0007155:cell adhesion

0019722:calcium-mediated signaling

0004950:chemokine receptor activity

0019957:C-C chemokine binding

PDB 1Y5D
Drugbank NA
KEGG hsa:1230

Related Compounds  (Total: 2)

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C0055
Name: Estradiol
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C1123
Name: trichosanthin


Related Herbs  (Total: 17)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0521 Tai Pan Zu Zhi Fen胎盘组织粉 NAHuman placenta
H0437 She Xiang麝香 AbelmuskMoschus moschiferus
H0235 Mao She Xiang毛麝香 AbelmuskMoschus moschiferus
H0661 Xiao Hei Dou小黑豆 Black turtle beanPhaseolus vulgaris
H0356 Ren Gong She Xiang人工麝香 AbelmuskMoschus moschiferus
H0380 San Qi Gan Jin Gao三七干浸膏 SanchiPanax notoginseng
H0382 San Qi Hua三七花 SanchiPanax notoginseng
H0381 San Qi Gao Fen三七膏粉 SanchiPanax notoginseng
H0383 San Qi Jing Ye三七茎叶 SanchiPanax notoginseng
H0236 Mao She Xiang Jin Gao毛麝香浸膏 AbelmuskMoschus moschiferus
H1102 Gu Sui Bu骨碎补 Fortune’s drynaria rhizomeDrynaria fortunei
H0077 Jiu EthanolVinum
H0384 San Qi Ye三七叶 Folium panax notoginsengPanax notoginseng
H0520 Tai Pan Fen胎盘粉 Fetus powderHuman placenta
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0385 San Qi Ye Jing三七叶茎 SanchiPanax notoginseng
H0847 Zi He Che紫河车 Human placentaHomo sapiens