HIT-result

Type	Detail
Target ID	T49USV
Protein Name	Nuclear receptor subfamily 0 group B member 2
Uniprot ID	Q15466
Protein Name Alias	Orphan nuclear receptor SHP; Small heterodimer partner
Gene ID	8431
Gene Symbol	NR0B2
Gene Alias	SHP
TTD	T89859: Research target
Pfam	PF00104
GO	0008203:cholesterol metabolic process 0005634:nucleus 0006367:transcription initiation from RNA polymerase II promoter 0007623:circadian rhythm 0032991:protein-containing complex 0003714:transcription corepressor activity 0045892:negative regulation of transcription, DNA-templated 0042803:protein homodimerization activity 0032922:circadian regulation of gene expression 0010628:positive regulation of gene expression 0005654:nucleoplasm 0010629:negative regulation of gene expression 0045893:positive regulation of transcription, DNA-templated 0043433:negative regulation of DNA-binding transcription factor activity 0046966:thyroid hormone receptor binding 0044877:protein-containing complex binding 0046965:retinoid X receptor binding 0140416:transcription regulator inhibitor activity 0031100:animal organ regeneration 0000122:negative regulation of transcription by RNA polymerase II 0045471:response to ethanol 0008134:transcription factor binding 0042975:peroxisome proliferator activated receptor binding 0009749:response to glucose 0015721:bile acid and bile salt transport 0007219:Notch signaling pathway 0019904:protein domain specific binding 0014070:response to organic cyclic compound 0032024:positive regulation of insulin secretion 0005737:cytoplasm 0000785:chromatin
PDB	5UFS ; 1YUC ; 6W9M ; 2Z4J ; 2Q3Y ; 4ONI ; 4DOR
Drugbank	NA
KEGG	hsa:8431

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Name: Bile Acid

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Name: Chenodiol

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0431	She Dan Zhi	蛇胆汁	Snake bile	Fel serpentis liquidum
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens