HIT-result

Type	Detail
Target ID	T56A9T
Protein Name	Tyrosine-protein kinase TXK
Uniprot ID	P42681
Protein Name Alias	EC 2.7.10.2; Protein-tyrosine kinase 4; Resting lymphocyte kinase
Gene ID	7294
Gene Symbol	TXK
Gene Alias	PTK4; RLK
TTD	T32590: Research target
Pfam	PF00017 ; PF00018 ; PF07714
GO	0005634:nucleus 0046777:protein autophosphorylation 0007202:activation of phospholipase C activity 0002250:adaptive immune response 0038083:peptidyl-tyrosine autophosphorylation 0010468:regulation of gene expression 0060335:positive regulation of interferon-gamma-mediated signaling pathway 0004713:protein tyrosine kinase activity 0050852:T cell receptor signaling pathway 0032729:positive regulation of interferon-gamma production 0005524:ATP binding 0005886:plasma membrane 0042246:tissue regeneration 0004715:non-membrane spanning protein tyrosine kinase activity 0007229:integrin-mediated signaling pathway 0001819:positive regulation of cytokine production 0010543:regulation of platelet activation 0006468:protein phosphorylation 0004714:transmembrane receptor protein tyrosine kinase activity 0005737:cytoplasm 0045944:positive regulation of transcription by RNA polymerase II
PDB	2DM0
Drugbank	DB12010 ; DB15035
KEGG	hsa:7294

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0629	Xi Xin	细辛	Siebold wildginger	Asarum sieboldii

Target Description