HIT-result

Target Description

Type	Detail
Target ID	T62G0S
Protein Name	Cofilin-1
Uniprot ID	P23528
Protein Name Alias	18 kDa phosphoprotein; p18; Cofilin, non-muscle isoform
Gene ID	1072
Gene Symbol	CFL1
Gene Alias	CFL
TTD	NA
Pfam	PF00241
GO	0048870:cell motility 0007266:Rho protein signal transduction 0016363:nuclear matrix 0051015:actin filament binding 0009615:response to virus 0005925:focal adhesion 0030043:actin filament fragmentation 0051293:establishment of spindle localization 0043066:negative regulation of apoptotic process 0031982:vesicle 0032587:ruffle membrane 0016020:membrane 0070062:extracellular exosome 0035722:interleukin-12-mediated signaling pathway 0005829:cytosol 0030036:actin cytoskeleton organization 0007010:cytoskeleton organization 0016032:viral process 0005615:extracellular space 0022604:regulation of cell morphogenesis 0061001:regulation of dendritic spine morphogenesis 0044794:positive regulation by host of viral process 0030042:actin filament depolymerization 0030027:lamellipodium 0031258:lamellipodium membrane 0005634:nucleus 0051014:actin filament severing 0015629:actin cytoskeleton 0005737:cytoplasm 0040019:positive regulation of embryonic development
PDB	6VAO ; 5HVK ; 6UC0 ; 4BEX ; 6UBY ; 3J0S ; 1Q8G ; 1Q8X ; 5L6W ; 6UC4
Drugbank	DB11638 ; DB04147 ; DB09130
KEGG	hsa:1072

Type

Detail

Target ID

T62G0S

Protein Name

Cofilin-1

Uniprot ID

P23528

Protein Name Alias

18 kDa phosphoprotein; p18; Cofilin, non-muscle isoform

Gene ID

1072

Gene Symbol

CFL1

Gene Alias

CFL

TTD

Pfam

PF00241

0048870:cell motility

0007266:Rho protein signal transduction

0016363:nuclear matrix

0051015:actin filament binding

0009615:response to virus

0005925:focal adhesion

0030043:actin filament fragmentation

0051293:establishment of spindle localization

0043066:negative regulation of apoptotic process

0031982:vesicle

0032587:ruffle membrane

0016020:membrane

0070062:extracellular exosome

0035722:interleukin-12-mediated signaling pathway

0005829:cytosol

0030036:actin cytoskeleton organization

0007010:cytoskeleton organization

0016032:viral process

0005615:extracellular space

0022604:regulation of cell morphogenesis

0061001:regulation of dendritic spine morphogenesis

0044794:positive regulation by host of viral process

0030042:actin filament depolymerization

0030027:lamellipodium

0031258:lamellipodium membrane

0005634:nucleus

0051014:actin filament severing

0015629:actin cytoskeleton

0005737:cytoplasm

0040019:positive regulation of embryonic development

PDB

6VAO ; 5HVK ; 6UC0 ; 4BEX ; 6UBY ; 3J0S ; 1Q8G ; 1Q8X ; 5L6W ; 6UC4

Drugbank

DB11638 ; DB04147 ; DB09130

KEGG

hsa:1072

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0235	Mao She Xiang	毛麝香	Abelmusk	Moschus moschiferus
H1102	Gu Sui Bu	骨碎补	Fortune’s drynaria rhizome	Drynaria fortunei
H0381	San Qi Gao Fen	三七膏粉	Sanchi	Panax notoginseng
H0384	San Qi Ye	三七叶	Folium panax notoginseng	Panax notoginseng
H0236	Mao She Xiang Jin Gao	毛麝香浸膏	Abelmusk	Moschus moschiferus
H0380	San Qi Gan Jin Gao	三七干浸膏	Sanchi	Panax notoginseng
H0437	She Xiang	麝香	Abelmusk	Moschus moschiferus
H0661	Xiao Hei Dou	小黑豆	Black turtle bean	Phaseolus vulgaris
H0521	Tai Pan Zu Zhi Fen	胎盘组织粉	NA	Human placenta
H0385	San Qi Ye Jing	三七叶茎	Sanchi	Panax notoginseng
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0356	Ren Gong She Xiang	人工麝香	Abelmusk	Moschus moschiferus
H0382	San Qi Hua	三七花	Sanchi	Panax notoginseng
H0520	Tai Pan Fen	胎盘粉	Fetus powder	Human placenta
H0383	San Qi Jing Ye	三七茎叶	Sanchi	Panax notoginseng
H0077	Jiu	酒	Ethanol	Vinum

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 17)