HIT-result

Target Description

Type	Detail
Target ID	T62TXV
Protein Name	GTP-binding protein Rheb
Uniprot ID	Q15382
Protein Name Alias	Ras homolog enriched in brain
Gene ID	6009
Gene Symbol	RHEB
Gene Alias	RHEB2
TTD	NA
Pfam	PF00071
GO	0019003:GDP binding 0070062:extracellular exosome 0007050:cell cycle arrest 0005789:endoplasmic reticulum membrane 0120163:negative regulation of cold-induced thermogenesis 0032008:positive regulation of TOR signaling 0048714:positive regulation of oligodendrocyte differentiation 0014069:postsynaptic density 0000139:Golgi membrane 0005765:lysosomal membrane 0019901:protein kinase binding 0005829:cytosol 0000287:magnesium ion binding 0005886:plasma membrane 0034198:cellular response to amino acid starvation 0003924:GTPase activity 0016020:membrane 2000074:regulation of type B pancreatic cell development 0007165:signal transduction 0005525:GTP binding 0007264:small GTPase mediated signal transduction 0005681:spliceosomal complex 0016241:regulation of macroautophagy
PDB	3SEA ; 7BTC ; 1XTR ; 6BSX ; 5YXH ; 6BCU ; 1XTQ ; 7BTA ; 7BTD ; 1XTS ; 3T5G ; 6BT0
Drugbank	DB04315 ; DB04137
KEGG	hsa:6009

Type

Detail

Target ID

T62TXV

Protein Name

GTP-binding protein Rheb

Uniprot ID

Q15382

Protein Name Alias

Ras homolog enriched in brain

Gene ID

6009

Gene Symbol

RHEB

Gene Alias

RHEB2

TTD

Pfam

PF00071

0019003:GDP binding

0070062:extracellular exosome

0007050:cell cycle arrest

0005789:endoplasmic reticulum membrane

0120163:negative regulation of cold-induced thermogenesis

0032008:positive regulation of TOR signaling

0048714:positive regulation of oligodendrocyte differentiation

0014069:postsynaptic density

0000139:Golgi membrane

0005765:lysosomal membrane

0019901:protein kinase binding

0005829:cytosol

0000287:magnesium ion binding

0005886:plasma membrane

0034198:cellular response to amino acid starvation

0003924:GTPase activity

0016020:membrane

2000074:regulation of type B pancreatic cell development

0007165:signal transduction

0005525:GTP binding

0007264:small GTPase mediated signal transduction

0005681:spliceosomal complex

0016241:regulation of macroautophagy

PDB

3SEA ; 7BTC ; 1XTR ; 6BSX ; 5YXH ; 6BCU ; 1XTQ ; 7BTA ; 7BTD ; 1XTS ; 3T5G ; 6BT0

Drugbank

DB04315 ; DB04137

KEGG

hsa:6009

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1134	Bai Jiang Can	白僵蚕	Silkworm larva	Bombyx mori
H0222	Man Tuo Luo	曼陀罗	Jimsonweed	Datura stramonium
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0215	Mai Ya	麦芽	Barley germinating fruit	Hordeum vulgare
H1041	Feng Qie Hua	枫茄花	Jimsonweed	Datura stramonium
H0495	Can Sha	蚕砂	Silkworm excrement	Bombyx mori
H0863	Zui Xian Tao	醉仙桃	jimsonweed	Datura stramonium
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera
H0490	Can Jian	蚕茧	Silk cocoon	Bombyx mori
H0476	Can E	蚕蛾	Silkworm	Bombyx mori
H0223	Man Tuo Luo Jin Gao	曼陀罗浸膏	Jimsonweed	Datura stramonium
H0500	Can Yong	蚕蛹	Silkworm chrysalis	Bombyx mori
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 13)