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Target Description
Type
Detail
Target ID
T64MZG
Protein Name
Tribbles homolog 3
Uniprot ID
Q96RU7
Protein Name Alias
TRB-3; Neuronal cell death-inducible putative kinase; SINK; p65-interacting inhibitor of NF-kappa-B
Gene ID
57761
Gene Symbol
TRIB3
Gene Alias
C20orf97; NIPK; SKIP3; TRB3
TTD
NA
Pfam
PF00069
GO
0005634:nucleus
0034976:response to endoplasmic reticulum stress
0019222:regulation of metabolic process
0051443:positive regulation of ubiquitin-protein transferase activity
0031625:ubiquitin protein ligase binding
0031434:mitogen-activated protein kinase kinase binding
0051897:positive regulation of protein kinase B signaling
0045892:negative regulation of transcription, DNA-templated
0019901:protein kinase binding
0010827:regulation of glucose transmembrane transport
0003714:transcription corepressor activity
0005829:cytosol
0070059:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0005524:ATP binding
0051898:negative regulation of protein kinase B signaling
0005886:plasma membrane
0045717:negative regulation of fatty acid biosynthetic process
0032092:positive regulation of protein binding
0043405:regulation of MAP kinase activity
0004860:protein kinase inhibitor activity
0006468:protein phosphorylation
0000122:negative regulation of transcription by RNA polymerase II
0032869:cellular response to insulin stimulus
0055106:ubiquitin-protein transferase regulator activity
0032436:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0005654:nucleoplasm
0010506:regulation of autophagy
0045599:negative regulation of fat cell differentiation
0006469:negative regulation of protein kinase activity
PDB
NA
Drugbank
NA
KEGG
hsa:57761
Related Compounds (Total: 2)
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C0213
Name: Metformin
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C0987
Name: Atorvastatin
Related Herbs (Total: 2)
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Herb id
Chinese Pin Yin
Chinese Character
English Name
Latin Name
H0360
Ren Zhong Bai
人中白
Human urine sediment
Homo sapiens
H0847
Zi He Che
紫河车
Human placenta
Homo sapiens