Target Description

Type Detail
Target ID T64MZG
Protein Name Tribbles homolog 3
Uniprot ID Q96RU7
Protein Name Alias TRB-3;  Neuronal cell death-inducible putative kinase;  SINK;  p65-interacting inhibitor of NF-kappa-B
Gene ID 57761
Gene Symbol TRIB3
Gene Alias C20orf97;  NIPK;  SKIP3;  TRB3
TTD NA
Pfam PF00069
GO
0005634:nucleus

0034976:response to endoplasmic reticulum stress

0019222:regulation of metabolic process

0051443:positive regulation of ubiquitin-protein transferase activity

0031625:ubiquitin protein ligase binding

0031434:mitogen-activated protein kinase kinase binding

0051897:positive regulation of protein kinase B signaling

0045892:negative regulation of transcription, DNA-templated

0019901:protein kinase binding

0010827:regulation of glucose transmembrane transport

0003714:transcription corepressor activity

0005829:cytosol

0070059:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

0005524:ATP binding

0051898:negative regulation of protein kinase B signaling

0005886:plasma membrane

0045717:negative regulation of fatty acid biosynthetic process

0032092:positive regulation of protein binding

0043405:regulation of MAP kinase activity

0004860:protein kinase inhibitor activity

0006468:protein phosphorylation

0000122:negative regulation of transcription by RNA polymerase II

0032869:cellular response to insulin stimulus

0055106:ubiquitin-protein transferase regulator activity

0032436:positive regulation of proteasomal ubiquitin-dependent protein catabolic process

0005654:nucleoplasm

0010506:regulation of autophagy

0045599:negative regulation of fat cell differentiation

0006469:negative regulation of protein kinase activity

PDB NA
Drugbank NA
KEGG hsa:57761

Related Compounds  (Total: 2)

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C0213
Name: Metformin
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C0987
Name: Atorvastatin


Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens