Target Description

Type Detail
Target ID T73ND5
Protein Name Myocilin
Uniprot ID Q99972
Protein Name Alias Myocilin 55 kDa subunit;  Trabecular meshwork-induced glucocorticoid response protein
Gene ID 4653
Gene Symbol MYOC
Gene Alias GLC1A;  TIGR
TTD NA
Pfam PF02191
GO
0032027:myosin light chain binding

0001953:negative regulation of cell-matrix adhesion

0014068:positive regulation of phosphatidylinositol 3-kinase signaling

0005109:frizzled binding

0070062:extracellular exosome

0001968:fibronectin binding

0062023:collagen-containing extracellular matrix

0030335:positive regulation of cell migration

0051496:positive regulation of stress fiber assembly

0033268:node of Ranvier

0051897:positive regulation of protein kinase B signaling

0031410:cytoplasmic vesicle

0045162:clustering of voltage-gated sodium channels

0035024:negative regulation of Rho protein signal transduction

0005615:extracellular space

0030971:receptor tyrosine kinase binding

0031175:neuron projection development

0060348:bone development

0038031:non-canonical Wnt signaling pathway via JNK cascade

0005783:endoplasmic reticulum

0014734:skeletal muscle hypertrophy

0038133:ERBB2-ERBB3 signaling pathway

0005741:mitochondrial outer membrane

0005758:mitochondrial intermembrane space

0001649:osteoblast differentiation

0051901:positive regulation of mitochondrial depolarization

0005794:Golgi apparatus

1900026:positive regulation of substrate adhesion-dependent cell spreading

0022011:myelination in peripheral nervous system

0051497:negative regulation of stress fiber assembly

0005743:mitochondrial inner membrane

0005791:rough endoplasmic reticulum

0046872:metal ion binding

0043408:regulation of MAPK cascade

0051894:positive regulation of focal adhesion assembly

0005929:cilium

PDB 4WXU ; 6OU2 ; 6PKD ; 4WXQ ; 4WXS ; 6OU0 ; 6PKE ; 6OU3 ; 6PKF ; 6OU1
Drugbank NA
KEGG hsa:4653

Related Compounds  (Total: 1)

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C0055
Name: Estradiol


Related Herbs  (Total: 17)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0521 Tai Pan Zu Zhi Fen胎盘组织粉 NAHuman placenta
H0077 Jiu EthanolVinum
H1102 Gu Sui Bu骨碎补 Fortune’s drynaria rhizomeDrynaria fortunei
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0382 San Qi Hua三七花 SanchiPanax notoginseng
H0236 Mao She Xiang Jin Gao毛麝香浸膏 AbelmuskMoschus moschiferus
H0661 Xiao Hei Dou小黑豆 Black turtle beanPhaseolus vulgaris
H0356 Ren Gong She Xiang人工麝香 AbelmuskMoschus moschiferus
H0520 Tai Pan Fen胎盘粉 Fetus powderHuman placenta
H0381 San Qi Gao Fen三七膏粉 SanchiPanax notoginseng
H0380 San Qi Gan Jin Gao三七干浸膏 SanchiPanax notoginseng
H0385 San Qi Ye Jing三七叶茎 SanchiPanax notoginseng
H0384 San Qi Ye三七叶 Folium panax notoginsengPanax notoginseng
H0383 San Qi Jing Ye三七茎叶 SanchiPanax notoginseng
H0437 She Xiang麝香 AbelmuskMoschus moschiferus
H0235 Mao She Xiang毛麝香 AbelmuskMoschus moschiferus
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens