Target Description

Type Detail
Target ID T74J8E
Protein Name Synaptic vesicular amine transporter
Uniprot ID Q05940
Protein Name Alias Monoamine transporter;  Solute carrier family 18 member 2;  Vesicular amine transporter 2;  VAT2
Gene ID 6571
Gene Symbol SLC18A2
Gene Alias SVMT;  VMAT2
TTD T48873: Successful target
Pfam PF07690
GO
0015844:monoamine transport

0009791:post-embryonic development

0009636:response to toxic substance

0008504:monoamine transmembrane transporter activity

1903427:negative regulation of reactive oxygen species biosynthetic process

0007626:locomotory behavior

0030672:synaptic vesicle membrane

0016020:membrane

0022857:transmembrane transporter activity

0005813:centrosome

0043231:intracellular membrane-bounded organelle

0042137:sequestering of neurotransmitter

0098691:dopaminergic synapse

0070083:clathrin-sculpted monoamine transport vesicle membrane

0001975:response to amphetamine

0006836:neurotransmitter transport

0015872:dopamine transport

0015842:aminergic neurotransmitter loading into synaptic vesicle

0043195:terminal bouton

0008021:synaptic vesicle

0005886:plasma membrane

0005335:serotonin:sodium symporter activity

0005887:integral component of plasma membrane

0098700:neurotransmitter loading into synaptic vesicle

0007268:chemical synaptic transmission

PDB NA
Drugbank DB00502 ; DB09363 ; DB01364 ; DB00182 ; DB01089 ; DB12161 ; DB00988 ; DB01442 ; DB04821 ; DB01472 ; DB00865 ; DB01577 ; DB01576 ; DB01454 ; DB06714 ; DB00206 ; DB00714 ; DB04844 ; DB00368 ; DB08839 ; DB01363 ; DB00579 ; DB05381 ; DB06706
KEGG hsa:6571

Related Compounds  (Total: 5)

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C0210
Name: Melatonin
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C0233
Name: (-)-Lobeline
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C0280
Name: Oxytocin
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C0997
Name: lobeline
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C1088
Name: reserpine


Related Herbs  (Total: 5)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0920 Da Ban Bian Lian大半边莲 Asian lobeliaLobelia chinensis
H0113 Ban Bian Lian半边莲 Chinese lobeliaLobelia chinensis
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens