Target Description

Type Detail
Target ID T74KF7
Protein Name RE1-silencing transcription factor
Uniprot ID Q13127
Protein Name Alias Neural-restrictive silencer factor;  X2 box repressor
Gene ID 5978
Gene Symbol REST
Gene Alias NRSF;  XBR
TTD NA
Pfam NA
GO
0043065:positive regulation of apoptotic process

2000706:negative regulation of dense core granule biogenesis

0005634:nucleus

0045892:negative regulation of transcription, DNA-templated

0045666:positive regulation of neuron differentiation

2000065:negative regulation of cortisol biosynthetic process

0002931:response to ischemia

0071257:cellular response to electrical stimulus

0097150:neuronal stem cell population maintenance

2000678:negative regulation of transcription regulatory region DNA binding

0045955:negative regulation of calcium ion-dependent exocytosis

0046676:negative regulation of insulin secretion

2000798:negative regulation of amniotic stem cell differentiation

0045944:positive regulation of transcription by RNA polymerase II

0045667:regulation of osteoblast differentiation

0003682:chromatin binding

0050768:negative regulation of neurogenesis

0000976:transcription regulatory region sequence-specific DNA binding

0003700:DNA-binding transcription factor activity

0070933:histone H4 deacetylation

0032348:negative regulation of aldosterone biosynthetic process

0008285:negative regulation of cell population proliferation

0010628:positive regulation of gene expression

1903203:regulation of oxidative stress-induced neuron death

0017053:transcription repressor complex

0035690:cellular response to drug

0043922:negative regulation by host of viral transcription

0005737:cytoplasm

0099563:modification of synaptic structure

0001666:response to hypoxia

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0006355:regulation of transcription, DNA-templated

0042802:identical protein binding

0010468:regulation of gene expression

0005654:nucleoplasm

2000740:negative regulation of mesenchymal stem cell differentiation

0001227:DNA-binding transcription repressor activity, RNA polymerase II-specific

1903223:positive regulation of oxidative stress-induced neuron death

0045893:positive regulation of transcription, DNA-templated

0060088:auditory receptor cell stereocilium organization

0045665:negative regulation of neuron differentiation

0050885:neuromuscular process controlling balance

1902459:positive regulation of stem cell population maintenance

0050910:detection of mechanical stimulus involved in sensory perception of sound

0000381:regulation of alternative mRNA splicing, via spliceosome

0008134:transcription factor binding

0035019:somatic stem cell population maintenance

0071385:cellular response to glucocorticoid stimulus

0005829:cytosol

0043280:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

0046872:metal ion binding

0010629:negative regulation of gene expression

0000122:negative regulation of transcription by RNA polymerase II

1903204:negative regulation of oxidative stress-induced neuron death

0060379:cardiac muscle cell myoblast differentiation

PDB 6DU2 ; 2CZY ; 6DU3
Drugbank NA
KEGG hsa:5978

Related Compounds  (Total: 1)

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C0305
Name: Phorbol Myristate Acetate


Related Herbs  (Total: 9)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0888 Ba Dou Ye巴豆叶 Pu rging crotonCroton tiglium
H1167 He Tao核桃 English walnut seedSemen juglandis
H0269 Mu Gua木瓜 Chinese floweringquinceChaenomeles sinensis
H1168 He Tao Ren核桃仁 English walnut seedSemen juglandis
H0582 Cao Dou Kou Ren草豆蔻仁 Katsumada galangalAlpinia katsumadai
H0484 Shui Fei Ji水飞蓟 St marysSilybum marianum
H0878 Ba Dou Shuang巴豆霜 Defatted croton seed powderCroton tiglium
H0869 Ba Dou巴豆 Pu rging crotonCroton tiglium
H0574 Cao Dou Kou草豆蔻 Katsumada galangalAlpinia katsumadai