Target Description

Type Detail
Target ID T78QVQ
Protein Name Myosin-7
Uniprot ID P12883
Protein Name Alias Myosin heavy chain 7;  Myosin heavy chain slow isoform;  MyHC-slow;  Myosin heavy chain, cardiac muscle beta isoform;  MyHC-beta
Gene ID 4625
Gene Symbol MYH7
Gene Alias MYHCB
TTD T07507: Clinical Trial target
Pfam PF00063 ; PF01576 ; PF02736
GO
0016887:ATPase activity

0000146:microfilament motor activity

0002026:regulation of the force of heart contraction

0003009:skeletal muscle contraction

0001725:stress fiber

0055010:ventricular cardiac muscle tissue morphogenesis

0060048:cardiac muscle contraction

0046034:ATP metabolic process

0030018:Z disc

0006936:muscle contraction

0014883:transition between fast and slow fiber

0051015:actin filament binding

0014728:regulation of the force of skeletal muscle contraction

0005524:ATP binding

0014898:cardiac muscle hypertrophy in response to stress

0031449:regulation of slow-twitch skeletal muscle fiber contraction

0005859:muscle myosin complex

0030898:actin-dependent ATPase activity

0032982:myosin filament

0006941:striated muscle contraction

0007512:adult heart development

0030017:sarcomere

0005516:calmodulin binding

0002027:regulation of heart rate

0016459:myosin complex

0030049:muscle filament sliding

0030016:myofibril

PDB 5WLQ ; 4XA3 ; 4PA0 ; 4XA1 ; 4XA4 ; 6PFP ; 5CJ0 ; 1IK2 ; 5WJB ; 2FXM ; 2FXO ; 4P7H ; 4XA6 ; 3DTP ; 4DB1 ; 5WLZ ; 5CJ1 ; 5WJ7 ; 5CJ4 ; 5CHX ; 5TBY ; 5WME ; 6PF2
Drugbank DB08378
KEGG hsa:4625

Related Compounds  (Total: 2)

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C0222
Name: Metoprolol
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C1115
Name: cocaine


Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens