Target Description
| Type | Detail |
|---|---|
| Target ID | T80ZO6 |
| Protein Name | 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase |
| Uniprot ID |
Q9UNU6 |
| Protein Name Alias | EC 1.14.14.139; 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase; CYPVIIIB1; Cytochrome P450 8B1; Sterol 12-alpha-hydroxylase |
| Gene ID |
1582 |
| Gene Symbol | CYP8B1 |
| Gene Alias | CYP12 |
| TTD | NA |
| Pfam | PF00067 |
| GO |
0038183:bile acid signaling pathway
0006699:bile acid biosynthetic process 0045797:positive regulation of intestinal cholesterol absorption 0070723:response to cholesterol 0016125:sterol metabolic process 0020037:heme binding 0008397:sterol 12-alpha-hydroxylase activity 0031667:response to nutrient levels 0019825:oxygen binding 0005506:iron ion binding 0016021:integral component of membrane 0005789:endoplasmic reticulum membrane |
| PDB | NA |
| Drugbank | NA |
| KEGG | hsa:1582 |
