HIT-result

Target Description

Type	Detail
Target ID	T82LND
Protein Name	Myoblast determination protein 1
Uniprot ID	P15172
Protein Name Alias	Class C basic helix-loop-helix protein 1; bHLHc1; Myogenic factor 3; Myf-3
Gene ID	4654
Gene Symbol	MYOD1
Gene Alias	BHLHC1; MYF3; MYOD
TTD	NA
Pfam	PF12232 ; PF01586 ; PF00010
GO	0005634:nucleus 1905382:positive regulation of snRNA transcription by RNA polymerase II 0048741:skeletal muscle fiber development 0042693:muscle cell fate commitment 0043967:histone H4 acetylation 0000381:regulation of alternative mRNA splicing, via spliceosome 0043484:regulation of RNA splicing 0000791:euchromatin 0030016:myofibril 0031625:ubiquitin protein ligase binding 0003682:chromatin binding 0043415:positive regulation of skeletal muscle tissue regeneration 0007517:muscle organ development 0035914:skeletal muscle cell differentiation 0014908:myotube differentiation involved in skeletal muscle regeneration 2000818:negative regulation of myoblast proliferation 0000977:RNA polymerase II transcription regulatory region sequence-specific DNA binding 0051149:positive regulation of muscle cell differentiation 0048743:positive regulation of skeletal muscle fiber development 0035562:negative regulation of chromatin binding 0031490:chromatin DNA binding 0007520:myoblast fusion 0001228:DNA-binding transcription activator activity, RNA polymerase II-specific 0071356:cellular response to tumor necrosis factor 0001102:RNA polymerase II activating transcription factor binding 0043503:skeletal muscle fiber adaptation 0000785:chromatin 1990841:promoter-specific chromatin binding 0051099:positive regulation of binding 0070888:E-box binding 0071385:cellular response to glucocorticoid stimulus 0035257:nuclear hormone receptor binding 0007518:myoblast fate determination 0045663:positive regulation of myoblast differentiation 0043966:histone H3 acetylation 0007519:skeletal muscle tissue development 0005667:transcription regulator complex 0014904:myotube cell development 0071453:cellular response to oxygen levels 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific 1901741:positive regulation of myoblast fusion 0006468:protein phosphorylation 0042803:protein homodimerization activity 0006357:regulation of transcription by RNA polymerase II 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0005654:nucleoplasm 1990837:sequence-specific double-stranded DNA binding 0045944:positive regulation of transcription by RNA polymerase II 0071392:cellular response to estradiol stimulus 0009267:cellular response to starvation
PDB	NA
Drugbank	NA
KEGG	hsa:4654

Type

Detail

Target ID

T82LND

Protein Name

Myoblast determination protein 1

Uniprot ID

P15172

Protein Name Alias

Class C basic helix-loop-helix protein 1; bHLHc1; Myogenic factor 3; Myf-3

Gene ID

4654

Gene Symbol

MYOD1

Gene Alias

BHLHC1; MYF3; MYOD

TTD

Pfam

PF12232 ; PF01586 ; PF00010

0005634:nucleus

1905382:positive regulation of snRNA transcription by RNA polymerase II

0048741:skeletal muscle fiber development

0042693:muscle cell fate commitment

0043967:histone H4 acetylation

0000381:regulation of alternative mRNA splicing, via spliceosome

0043484:regulation of RNA splicing

0000791:euchromatin

0030016:myofibril

0031625:ubiquitin protein ligase binding

0003682:chromatin binding

0043415:positive regulation of skeletal muscle tissue regeneration

0007517:muscle organ development

0035914:skeletal muscle cell differentiation

0014908:myotube differentiation involved in skeletal muscle regeneration

2000818:negative regulation of myoblast proliferation

0000977:RNA polymerase II transcription regulatory region sequence-specific DNA binding

0051149:positive regulation of muscle cell differentiation

0048743:positive regulation of skeletal muscle fiber development

0035562:negative regulation of chromatin binding

0031490:chromatin DNA binding

0007520:myoblast fusion

0001228:DNA-binding transcription activator activity, RNA polymerase II-specific

0071356:cellular response to tumor necrosis factor

0001102:RNA polymerase II activating transcription factor binding

0043503:skeletal muscle fiber adaptation

0000785:chromatin

1990841:promoter-specific chromatin binding

0051099:positive regulation of binding

0070888:E-box binding

0071385:cellular response to glucocorticoid stimulus

0035257:nuclear hormone receptor binding

0007518:myoblast fate determination

0045663:positive regulation of myoblast differentiation

0043966:histone H3 acetylation

0007519:skeletal muscle tissue development

0005667:transcription regulator complex

0014904:myotube cell development

0071453:cellular response to oxygen levels

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

1901741:positive regulation of myoblast fusion

0006468:protein phosphorylation

0042803:protein homodimerization activity

0006357:regulation of transcription by RNA polymerase II

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0005654:nucleoplasm

1990837:sequence-specific double-stranded DNA binding

0045944:positive regulation of transcription by RNA polymerase II

0071392:cellular response to estradiol stimulus

0009267:cellular response to starvation

PDB

Drugbank

KEGG

hsa:4654

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0521	Tai Pan Zu Zhi Fen	胎盘组织粉	NA	Human placenta
H0077	Jiu	酒	Ethanol	Vinum
H1102	Gu Sui Bu	骨碎补	Fortune’s drynaria rhizome	Drynaria fortunei
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0382	San Qi Hua	三七花	Sanchi	Panax notoginseng
H0236	Mao She Xiang Jin Gao	毛麝香浸膏	Abelmusk	Moschus moschiferus
H0661	Xiao Hei Dou	小黑豆	Black turtle bean	Phaseolus vulgaris
H0356	Ren Gong She Xiang	人工麝香	Abelmusk	Moschus moschiferus
H0520	Tai Pan Fen	胎盘粉	Fetus powder	Human placenta
H0381	San Qi Gao Fen	三七膏粉	Sanchi	Panax notoginseng
H0380	San Qi Gan Jin Gao	三七干浸膏	Sanchi	Panax notoginseng
H0385	San Qi Ye Jing	三七叶茎	Sanchi	Panax notoginseng
H0384	San Qi Ye	三七叶	Folium panax notoginseng	Panax notoginseng
H0383	San Qi Jing Ye	三七茎叶	Sanchi	Panax notoginseng
H0437	She Xiang	麝香	Abelmusk	Moschus moschiferus
H0235	Mao She Xiang	毛麝香	Abelmusk	Moschus moschiferus
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 17)