Target Description

Type Detail
Target ID T83RFH
Protein Name Protein S100-A9
Uniprot ID P06702
Protein Name Alias Calgranulin-B;  Calprotectin L1H subunit;  Leukocyte L1 complex heavy chain;  Migration inhibitory factor-related protein 14;  MRP-14;  p14;  S100 calcium-binding protein A9
Gene ID 6280
Gene Symbol S100A9
Gene Alias CAGB;  CFAG;  MRP14
TTD T38431: Clinical Trial target
Pfam PF01023
GO
0005634:nucleus

0018119:peptidyl-cysteine S-nitrosylation

0035606:peptidyl-cysteine S-trans-nitrosylation

2001244:positive regulation of intrinsic apoptotic signaling pathway

0070062:extracellular exosome

0062023:collagen-containing extracellular matrix

0010976:positive regulation of neuron projection development

0005829:cytosol

0051493:regulation of cytoskeleton organization

0035425:autocrine signaling

0016209:antioxidant activity

0006915:apoptotic process

0051092:positive regulation of NF-kappaB transcription factor activity

0005737:cytoplasm

0008017:microtubule binding

0005509:calcium ion binding

0002224:toll-like receptor signaling pathway

0005615:extracellular space

0019730:antimicrobial humoral response

0070488:neutrophil aggregation

0002544:chronic inflammatory response

0045113:regulation of integrin biosynthetic process

0030054:cell junction

0005886:plasma membrane

0006914:autophagy

0050786:RAGE receptor binding

0035821:modulation of process of other organism

0005856:cytoskeleton

0007267:cell-cell signaling

0043312:neutrophil degranulation

0050729:positive regulation of inflammatory response

0050832:defense response to fungus

0014002:astrocyte development

0006954:inflammatory response

0035662:Toll-like receptor 4 binding

0005576:extracellular region

0008270:zinc ion binding

0030307:positive regulation of cell growth

0048306:calcium-dependent protein binding

0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process

0061844:antimicrobial humoral immune response mediated by antimicrobial peptide

0005654:nucleoplasm

0032496:response to lipopolysaccharide

0032119:sequestering of zinc ion

0034774:secretory granule lumen

0042742:defense response to bacterium

0050544:arachidonic acid binding

0030593:neutrophil chemotaxis

0002523:leukocyte migration involved in inflammatory response

0045087:innate immune response

PDB 5W1F ; 6DS2 ; 4GGF ; 1XK4 ; 4XJK ; 1IRJ ; 5I8N
Drugbank DB01593 ; DB14533 ; DB14487 ; DB14548 ; DB01373
KEGG hsa:6280

Related Compounds  (Total: 1)

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C0305
Name: Phorbol Myristate Acetate


Related Herbs  (Total: 9)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0888 Ba Dou Ye巴豆叶 Pu rging crotonCroton tiglium
H1167 He Tao核桃 English walnut seedSemen juglandis
H0269 Mu Gua木瓜 Chinese floweringquinceChaenomeles sinensis
H1168 He Tao Ren核桃仁 English walnut seedSemen juglandis
H0582 Cao Dou Kou Ren草豆蔻仁 Katsumada galangalAlpinia katsumadai
H0484 Shui Fei Ji水飞蓟 St marysSilybum marianum
H0878 Ba Dou Shuang巴豆霜 Defatted croton seed powderCroton tiglium
H0869 Ba Dou巴豆 Pu rging crotonCroton tiglium
H0574 Cao Dou Kou草豆蔻 Katsumada galangalAlpinia katsumadai