Target Description
| Type | Detail |
|---|---|
| Target ID | T84C2C |
| Protein Name | Protein Tob1 |
| Uniprot ID |
P50616 |
| Protein Name Alias | Transducer of erbB-2 1 |
| Gene ID |
10140 |
| Gene Symbol | TOB1 |
| Gene Alias | TOB; TROB1 |
| TTD | NA |
| Pfam | PF07742 |
| GO |
0005634:nucleus
0017148:negative regulation of translation 0060213:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 0060390:regulation of SMAD protein signal transduction 0008285:negative regulation of cell population proliferation 0005737:cytoplasm 0060212:negative regulation of nuclear-transcribed mRNA poly(A) tail shortening 1900153:positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 0003714:transcription corepressor activity 0010468:regulation of gene expression 0046332:SMAD binding 0030014:CCR4-NOT complex 0030514:negative regulation of BMP signaling pathway 0045668:negative regulation of osteoblast differentiation 0030971:receptor tyrosine kinase binding |
| PDB | 5CI9 ; 5CI8 ; 2D5R ; 2Z15 |
| Drugbank | NA |
| KEGG | hsa:10140 |
Related Herbs (Total: 1)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0629 | Xi Xin | 细辛 | Siebold wildginger | Asarum sieboldii |