HIT-result

Type	Detail
Target ID	T85J2J
Protein Name	B2 bradykinin receptor
Uniprot ID	P30411
Protein Name Alias	B2R; BK-2 receptor
Gene ID	624
Gene Symbol	BDKRB2
Gene Alias	BKR2
TTD	T23714: Successful target
Pfam	PF00001
GO	0043114:regulation of vascular permeability 0007204:positive regulation of cytosolic calcium ion concentration 0007169:transmembrane receptor protein tyrosine kinase signaling pathway 0004947:bradykinin receptor activity 0019229:regulation of vasoconstriction 0050482:arachidonic acid secretion 1902239:negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 0008015:blood circulation 0033137:negative regulation of peptidyl-serine phosphorylation 0042310:vasoconstriction 0006939:smooth muscle contraction 0042311:vasodilation 0005887:integral component of plasma membrane 0005886:plasma membrane 0043231:intracellular membrane-bounded organelle 0002020:protease binding 0004930:G protein-coupled receptor activity 0009651:response to salt stress 0006954:inflammatory response 0004435:phosphatidylinositol phospholipase C activity 0005794:Golgi apparatus 0007186:G protein-coupled receptor signaling pathway 0046982:protein heterodimerization activity 0007166:cell surface receptor signaling pathway 0005768:endosome 0031702:type 1 angiotensin receptor binding
PDB	NA
Drugbank	DB05038 ; DB06196 ; DB06549
KEGG	hsa:624

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1205	Hu Lu Cha	葫芦茶	Triquetrous tadehagi	Tadehagi triquetrum
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description